A pan-cancer analysis of ABI3BP: a potential biomarker for prognosis and immunoinfiltration.

Objective: ABI Family Member 3 Binding Protein (ABI3BP) is an extracellular matrix protein that affects the carcinogenesis of lung and esophageal cancer. However, the relevance of ABI3BP in different forms of cancer is uncertain.

Methods: ABI3BP expression was interpreted using the Cancer Genome Atlas (TCGA) database, the Genotype Tissue Expression Atlas (GTEx) database, the Human Protein Atlas (HPA) database, the Cancer Cell Line Encyclopedia (CCLE) database, and immunohistochemistry.

A Psychological Intervention Program for Patients with Cerebral Infarction.

Introduction: Cerebral infarction is one of the most common cerebrovascular diseases. The sequelae caused by cerebral infarction, including limb paralysis, crooked mouth corners, language barriers, etc., seriously affect the patient's physical and mental health and enthusiasm for rehabilitation training.

Role of Wnt/-Catenin Signaling in the Chemoresistance Modulation of Colorectal Cancer.

Colorectal cancer (CRC) is a common malignancy with high morbidity and mortality worldwide. To date, chemotherapy plays an important role in the treatment of CRC patients. Multidrug resistance (MDR) is one of the major hurdles in chemotherapy for CRC, and the underlying mechanisms need to be explored.

Perioperative application of midline catheter and PICC in Patients with gastrointestinal tumors.

Purpose: This study aimed to compare the application value of midline catheter and peripherally inserted central catheter (PICC) in patients with gastrointestinal tumors during the perioperative period.

Methods: 487 patients with gastrointestinal tumors admitted to Qingdao Municipal Hospital from August 2016 to September 2018 were selected and retrospectively analyzed. 279 patients treated with midline catheters during the treatment were regarded as the study group, and another 208 patients treated with PICC were regarded as the control group.

Hybrid method to solve HP model on 3D lattice and to probe protein stability upon amino acid mutations.

Background: Predicting protein structure from amino acid sequence is a prominent problem in computational biology. The long range interactions (or non-local interactions) are known as the main source of complexity for protein folding and dynamics and play the dominant role in the compact architecture. Some simple but exact model, such as HP model, captures the pain point for this difficult problem and has important implications to understand the mapping between protein sequence and structure.