Publications by authors named "Fengyao Liu"
Article Synopsis
- Mental stress-induced myocardial ischemia (MSIMI) significantly increases cardiovascular events, yet its precise mechanisms related to myocardial blood flow (MBF) are not fully understood.
- A study using cardiac positron emission tomography (PET-CT) revealed that women with angina but no obstructive coronary artery disease (ANOCA) had a much higher prevalence of MSIMI compared to healthy controls.
- Results showed that these participants had lower MBF and coronary flow reserves, indicating that impaired coronary microvascular function plays a crucial role in the development of MSIMI in individuals with ANOCA.
Article Synopsis
- Depression and high-sensitivity C-reactive protein (hs-CRP) are linked to worse outcomes in coronary heart disease (CHD) patients, but their combined effects had not been well-studied before this research.
- The study assessed 414 CHD patients over two years using tools to measure depression and anxiety, finding that those with both elevated depression and high hs-CRP faced significantly higher risks of noncardiac readmissions and other adverse events.
- While high hs-CRP alone was associated with increased risks, elevated anxiety did not significantly impact patient outcomes, and no interactions between depression or anxiety and hs-CRP were found.
Background: Long COVID-19 is characterized by systemic deterioration of the entire body, leading to significant physical and mental disorders. Exercise training has the potential to improve persistent symptoms and cardiopulmonary functions.
Method: This was a single-center, randomized, controlled trial.
Article Synopsis
- - Sarcopenia, the age-related loss of muscle mass and strength, is linked to worse outcomes in chronic heart failure patients, but its effects on those with acute decompensated heart failure (ADHF) are not well-studied.
- - This research aims to enroll around 500 adults hospitalized for ADHF, assessing various outcomes like all-cause mortality and quality of life over a follow-up period of up to 2 years.
- - The findings could enhance understanding of how sarcopenia influences prognosis in ADHF patients, potentially leading to better risk assessment and management strategies in clinical settings.
Background: Angina with no obstructive coronary disease (ANOCA) and ischemia with no obstructive coronary disease, prevalent yet underrecognized conditions, mostly affect women. Previous studies rarely distinguished between them. We aimed to compare the prevalence of objective ischemia through various examinations in women with ANOCA and assess the impact of objective and subjective ischemia on their mental health.
View Article and Find Full Text PDFObjectives: To explore the long-term trends in unhealthy lifestyle factors and the risk sociodemographic subgroups among people with dyslipidemia.
Methods: Data extracted from the 1999 to 2018 National Health and Nutrition Examination Survey (NHANES). Lifestyle factors were smoking status, alcohol drinking, obesity, dietary quality, depression, physical activity, and sedentary behavior.
Purpose: Mental stress induced myocardial ischemia (MSIMI) is regarded as the primary cause of the angina with no obstructive coronary artery disease (ANOCA). Obstructive sleep apnea (OSA) is autonomously linked to obstructive coronary heart disease, hypertension, and sudden cardiac death. Similar to the impact of psychological stress on the cardiovascular system, individuals with OSA experience periodic nocturnal hypoxia, resulting in the activation of systemic inflammation, oxidative stress, endothelial dysfunction, and sympathetic hyperactivity.
View Article and Find Full Text PDFBackground: The utility of radionuclide myocardial perfusion imaging including positron emission tomography (PET) for diagnosing mental stress-induced myocardial ischemia (MSIMI) is clinically restricted. This study aims to assess the diagnostic performance of novel echocardiographic techniques, including automated strain and quantitative myocardial contrast echocardiography (MCE) with dedicated software and deep neural network model, for MSIMI detection. The secondary objective was to explore the correlation between changes in myocardial blood flow and MSIMI.
View Article and Find Full Text PDFIntroduction: Perioperative rehabilitation (PORT) has shown a positive effect on patients undergoing cardiac surgery. However, there are minimal data on the impact of short-term PORT in cardiac surgery, which is associated with higher postoperative morbidity and mortality. The trial will assess the efficacy of short-term PORT in reducing in-hospital mortality, postoperative pulmonary complications and length of stay, compared with the usual care in cardiac surgical patients.
View Article and Find Full Text PDFPrognosis value of EAS index in patients with obstructive coronary artery disease.
Quant Imaging Med Surg
September 2023
Article Synopsis
- The study investigates the effectiveness of the EAS index as a way to predict major adverse cardiovascular events (MACE) among patients with coronary artery disease (CAD), alongside traditional measures like left ventricular ejection fraction (LVEF).
- Researchers analyzed data from 477 CAD patients and found that a higher EAS index is linked to a greater risk of experiencing MACE within six months.
- Findings suggest that the EAS index could serve as a valuable tool for assessing risk in CAD patients, particularly for those with better cardiac function (LVEF ≥50%).
Article Synopsis
- Existing studies did not clearly distinguish the impacts of heavy metal exposure from those of physical activity (PA) on cardiovascular disease (CVD) risk, leaving a gap in understanding their interactive effects.
- A study involving 12,280 participants found that low blood levels of cadmium (Cd) and lead (Pb) were associated with a higher prevalence of CVD, with a stronger link to Cd; meanwhile, increased physical activity significantly reduced CVD risk.
- The research indicates that regular physical activity might mitigate the negative effects of Cd exposure on CVD risk, highlighting the importance of maintaining an active lifestyle for heart health.*
Article Synopsis
- - The study aimed to analyze national trends in unhealthy lifestyle factors, like diet and obesity, among US adults with cardiovascular disease (CVD) from 1999 to 2018, using data from the National Health and Nutrition Examination Survey (NHANES).
- - Findings showed smoking rates remained stable, but poor diet prevalence decreased, obesity rates increased significantly, and there was a rise in depression levels among participants with CVD over the two decades.
- - Sociodemographic factors such as low income and education levels were associated with higher rates of unhealthy lifestyle factors, indicating that these groups may be at greater risk for adverse health outcomes related to CVD.
Article Synopsis
- Unhealthy lifestyle factors, such as smoking and obesity, are significant risk factors for stroke and affect secondary prevention efforts; understanding these trends can help shape public health policy.
- The study analyzed data from the National Health and Nutrition Examination Surveys (NHANES) from 1999 to 2018, focusing on adults with a history of stroke to track lifestyle changes over time.
- Key findings included significant increases in alcohol consumption and obesity rates, a decrease in physical inactivity, and fluctuations in diet quality, while smoking and depression rates remained stable; stress factors like marital status and employment status were linked to these unhealthy lifestyle trends.
Gender Differences in Unhealthy Lifestyle Behaviors among Adults with Diabetes in the United States between 1999 and 2018.
Int J Environ Res Public Health
December 2022
Lifestyle management is important to patients with diabetes, but whether gender differences exist in lifestyle management is unclear. Data from the US National Health and Nutrition Examination Survey (NHANES 1999 to 2018) was used for this research. Gender differences were evaluated descriptively and using an odds ratio (OR) with a 95% confidence interval (CI).
View Article and Find Full Text PDFObjective: The aim of this study was to explore the different predictive values of depression among patients with different cardiac systolic function levels.
Methods: Four hundred eighty-three consecutive patients with obstructive coronary artery disease (CAD) were included the depressive state was assessed using the Chinese version of the Patient Health Questionnaire 9 (PHQ-9). Depression was defined as have depressive symptoms with a PHQ-9 score ≥5.
Introduction: Unhealthy lifestyle factors are known to increase the risk of chronic kidney disease (CKD) and its complications. The long-term trends in these factors are unclear.
Methods: The aim of the study was to assess temporal trends in the prevalence of risk factors in adults with CKD in the USA and identify sociodemographic subgroups at most risk.
Aim: Exploring the risk factors of prognosis in patients undergoing percutaneous coronary intervention (PCI) is of great importance. Our aim of the study is to investigate the association between variability in total cholesterol (TC) level and major adverse cardiovascular and cerebrovascular events (MACCE) in patients after PCI.
Methods: Between April 2004 and December 2009, 909 patients who underwent primary PCI and with at least three TC values were included in the final study.
Article Synopsis
- The study aimed to explore the link between perceived stress and coagulation function in patients with coronary heart disease (CHD) and assess their impact on clinical outcomes.
- It used the Perceived Stress Scale (PSS-10) to evaluate stress levels and measured coagulation factors like APTT, finding that higher stress scores were associated with shorter APTT times.
- Results suggest that perceived stress and APTT can predict cardiovascular outcomes, indicating that mental stress may influence coagulation and contribute to cardiovascular events in CHD patients.*
Background: Depression and anxiety are two common mood problems among patients with cardiovascular disease (CVD) and are associated with poor cardiac prognoses. The comorbidity of depression and anxiety is considered to be a more severe psychological status than non-comorbid mood disorders. However, little is known about the relationship between depression or anxiety and noncardiac readmission.
View Article and Find Full Text PDFMicroRNAs (miRs) regulate diverse biological functions in both normal and pathological cellular conditions by post-transcriptional regulation of various genes expression. Nevertheless, the role of miRs in regulating the protective functions of omega-3 fatty acid in relation to hypoxia in cardiomyocytes remains unknown. The aim of this study was to investigate the effects of omega-3 fatty acid supplementation on cardiomyocyte apoptosis and further delineate the mechanisms underlying microRNA-210 (miRNA-210)-induced cardiomyocyte apoptosis in vitro.
View Article and Find Full Text PDFObjectives: Depression and malnutrition are prevalent among people with coronary artery disease (CAD) and can affect their prognosis, but the relationship between depression and malnutrition and its co-effect on prognosis is not clear. We sought to explore that relationship and its effects.
Methods: In this study, the nutritional and emotional statuses of 547 people with CAD were assessed using the Controlling Nutritional Status (CONUT) score and the Patient Health Questionnaire-9.
Mental stress-induced myocardial ischemia (MSIMI) has attracted increasing attention in the last 30 y. Positron emission tomography/computed tomography (PET/CT) is among the most accurate methods for evaluating myocardial perfusion. Even so, echocardiography seems to be a more harmless option when the radiation exposure and high expense of PET/CT are considered.
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