Publications by authors named "Fengxia Wu"

Helicoid metal nanoparticles with intrinsic chirality have unveiled tailorable properties and unlocked many chirality-related applications across various fields. Nevertheless, the existing strategies for enantioselective synthesis of helicoid metal nanoparticles have been predominantly limited to gold. Here, we demonstrate a robust and versatile strategy for the enantioselective synthesis of helicoid nanoparticles beyond gold, leveraging chiral nanoconfinement provided by chiral SiO or nanoshells.

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Background: Night sweats are a condition in which an individual sweats excessively during sleep without awareness, and stops when they wake up. Prolonged episodes of night sweats might result in the depletion of trace elements and nutrients, affecting the growth and development of children.

Purpose: To investigate the relationship between sweat nights and season.

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Optical information encryption technology has garnered significant attention in currency security, information protection, and personal identification. While optical metasurfaces are considered ideal platforms for information encryption, their high cost and time-intensive fabrication processes have limited their widespread applications. To address this, emergent chiroptical nanomaterials offer new opportunities for information encryption through their polarization capabilities.

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The disproportionate expansion of telencephalic structures during human evolution involved tradeoffs that imposed greater connectivity and metabolic demands on midbrain dopaminergic neurons. Despite the central role of dopaminergic neurons in human-enriched disorders, molecular specializations associated with human-specific features and vulnerabilities of the dopaminergic system remain unexplored. Here, we establish a phylogeny-in-a-dish approach to examine gene regulatory evolution by differentiating pools of human, chimpanzee, orangutan, and macaque pluripotent stem cells into ventral midbrain organoids capable of forming long-range projections, spontaneous activity, and dopamine release.

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Helicoid plasmonic nanoparticles with intrinsic chirality are an emerging class of artificial chiral materials with tailorable properties. The ability to extend their chiroplasmonic responses to the near-infrared (NIR) range is critically important for biomedical and nanophotonic applications, yet the rational design of such materials remains challenging. Herein, a strategy employing chiral plasmon-dielectric coupling is proposed to manipulate the chiroptical responses into the NIR region with high optical anisotropy.

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The chiral discrimination of enantiomers is crucial for drug screening and agricultural production. Surface-enhanced Raman scattering (SERS) is proposed for discriminating enantiomers benefiting from chiral plasmonic materials. However, the mechanism of enantioselective SERS is unclear, and fluctuating SERS intensities may result in errors.

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Acute myeloid leukemia (AML) is the most common form of leukemia among adults and is characterized by uncontrolled proliferation and clonal expansion of hematopoietic cells. There has been a significant improvement in the treatment of younger patients, however, prognosis in the elderly AML patients remains poor. We used computational methods and machine learning (ML) techniques to identify and explore the differential high-risk genes (DHRGs) in AML.

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Heterodimers of metal nanocrystals (NCs) with tailored elemental distribution have emerged as promising candidates in the field of electrocatalysis, owing to their unique structures featuring heterogeneous interfaces with distinct components. Despite this, the rational synthesis of heterodimer NCs with similar elemental composition remains a formidable challenge, and their impact on electrocatalysis has remained largely elusive. In this study, Pd@Bi-PdBi heterodimer NCs are synthesized through an underpotential deposition (UPD)-directed growth pathway.

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Non-invasive detection of hemoglobin (Hb) concentration is of great clinical value for health screening and intraoperative blood transfusion. However, the accuracy and stability of non-invasive detection still need to be improved to meet clinical requirement. This paper proposes a non-invasive Hb detection method using ensemble extreme learning machine (EELM) regression based on eight-wavelength PhotoPlethysmoGraphic (PPG) signals.

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CO-stripping experiments are employed as a highly structure-sensitive and strategy to explore the mechanisms of plasmon-enhanced electrooxidation reactions. By using Pt-Au heterodimers as a model catalyst, the plasmon-induced current and potential changes on Pt and Au sites can be identified and explained.

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The occurrence of Phaeocystis globosa, a harmful algal bloom species in Chinese coastal waters, has significant impacts on marine organisms and poses a threat to the safety of coastal nuclear power plants. Although previous studies have established a close association between P. globosa blooms and the bacterial community, the relationship between the microeukaryotic community and P.

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Acute myeloid leukemia (AML) is a highly heterogeneous malignant disease of the blood cell. The current therapies for AML are unsatisfactory and the molecular mechanisms underlying AML are unclear. 5-methylcytosine (m5C) is an important posttranscriptional modification of mRNA, and is involved in the regulation of mRNA stability, translation, and other aspects of RNA metabolism.

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The application of surface plasmons in heterogeneous catalysis has attracted widespread attention due to their promising potential for harvesting solar energy. The effect of surface adsorbates on catalysts has been well documented in many traditional reactions; nonetheless, their role in plasmonic catalysis has been rarely studied. In this study, an electrochemical surface cleaning strategy is developed and the influence of surface adsorbates on plasmon-enhanced electrochemistry is investigated.

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Background: Due to environmental pollution, changes in lifestyle, and advancements in diagnostic technology, the prevalence of asthma has been increasing over the years. Although China has made early efforts in asthma epidemiology and prevention, there is still a lack of unified and comprehensive epidemiological research within the country. The objective of the study is to determine the nationwide prevalence distribution of asthma using the Baidu Index and China's Health Statistical Yearbook.

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The ecologically important marine phytoplankton group coccolithophores have a global distribution. The impacts of ocean acidification on the cosmopolitan species have received much attention and have been intensively studied. However, the species-specific responses of coccolithophores and how these responses will be regulated by other environmental drivers are still largely unknown.

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Periodontitis is a biofilm-related disease characterized by damage to the periodontal tissue and the development of systemic diseases. However, treatment of periodontitis remains unsatisfactory, especially with deep-tissue infections. This study describes rationally designed multifunctional photothermocatalytic agents for near-infrared-II light-mediated synergistic antibiofilm treatment, through modification of Lu-BiTe with FeO and poly(ethylene glycol)-b-poly(l-arginine) (PEG-b-PArg).

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The growing demand for highly active nanozymes in various fields has led to the development of several strategies to enhance their activity. Plasmonic enhancement, a strategy used in heterogenous catalysis, represents a promising strategy to boost the activity of nanozymes. Herein, Pd-Au heteromeric nanoparticles (Pd-Au dimers) with well-defined heterointerfaces have been explored as plasmonic nanozymes.

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Surface roughness in chiral plasmonic nanostructures generates asymmetrical localized electromagnetic fields, which hold great promise for applications in chiral recognition, chiroptical spectroscopic sensing, and enantioselective photocatalysis. In this study, we develop a surface topographical engineering approach to precisely manipulate the surface structures of chiral Au nanocrystals. Through carefully controlling the amounts of l- or d-cystine (Cys) and the seed solution in the growth process, we successfully synthesize chiral Au nanocrystals with highly disordered, ordered, and less ordered wrinkled surfaces.

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Metal helicoid nanoparticles with intrinsic 3D chiral structures have emerged as a new class of plasmonic metamaterials with outstanding chiroplasmonic properties. Despite the considerable potential of metal helicoid nanoparticles in chiroplasmonic sensing, their sensing capabilities remain elusive, stressing the need for the rational chirality engineering of helicoid nanoparticles. In this report, Au@Pd helicoid nanoparticles with engineered chiroplasmonic properties and integrated hydrogen sensing capabilities are rationally synthesized.

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Article Synopsis
  • This study aimed to identify the genetic causes of empty follicle syndrome (EFS) in women experiencing primary infertility.
  • Researchers performed whole exome sequencing on four affected women and discovered a harmful homozygous variant in the LHCGR gene, which was not present in a control group of 100 healthy individuals.
  • The findings suggest that this new variant contributes to female sterility and highlights the importance of genetic testing for LHCGR mutations in women with EFS.
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Incorporation of oxophilic metals into Pd-based nanostructures has shown great potential in small molecule electrooxidation owing to their superior anti-poisoning capability. However, engineering the electronic structure of oxophilic dopants in Pd-based catalysts remains challenging and their impact on electrooxidation reactions is rarely demonstrated. Herein, we have developed a method for synthesizing PdSb-based nanosheets, enabling the incorporation of the Sb element in a predominantly metallic state despite its high oxophilic nature.

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Metal-organic gels (MOGs) are a category of metal-organic smart soft materials with large specific surface areas, loose porous structures, and open metal active sites. In this work, trimetallic Fe(III)Co(II)Ni(II)-based MOGs (FeCoNi-MOGs) were synthesized at room temperature via a simple and mild one-step procedure. Fe, Co, and Ni were the three central metal ions in it, while 1,3,5-benzenetricarboxylic acid (HBTC) served as the ligand.

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The key to the application of direct methanol fuel cells is to improve the activity and durability of Pt-based catalysts. Based on the upshift of the d-band centre and exposure to more Pt active sites, PtPdTe catalysts with significantly enhanced electrocatalytic performance for the methanol oxidation reaction (MOR) were designed in this study. A series of different PtPdTe ( = 0.

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Metallic heterogeneous nanostructures with plasmonic functionality have attracted great attention in the field of plasmon-enhanced electrocatalysis, where surface plasmons produced under light excitation could facilitate the overall electrocatalytic performances. Owing to their controllability, multifunctionality, and complexity, heterogeneous metallic nanostructures take advantages of the properties from individual components and synergistic effects from adjacent components, thus may achieve remarkable electrocatalytic performances. This review highlights the state-of-the-art progress of the application of metallic heterostructures for plasmon-enhanced electrocatalysis.

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Fluorescence bioimaging based on rare-earth-doped nanocrystals (RENCs) in the shortwave infrared (SWIR, 1000-3000 nm) region has aroused intense interest due to deeper penetration depth and clarity. However, their downshifting emission rarely shows sufficient brightness beyond 1600 nm, especially in NIR-IIc. Here, we present a class of thulium (Tm) self-sensitized RENC fluorescence probes that exhibit bright downshifting luminescence at 1600-2100 nm (NIR-IIb/c) for in vivo bioimaging.

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