High spatial-resolved source-specific exposure and risk in the city scale: Influence of spatial interrelationship between PM sources and population on exposure.

Research on High Spatial-Resolved Source-Specific Exposure and Risk (HSRSSER) was conducted based on multiple-year, multiple-site synchronous measurement of PM-bound (particulate matter with aerodynamic diameter<2.5 μm) toxic components in a Chinese megacity. The developed HSRSSER model combined the Positive Matrix Factorization (PMF) and Land Use Regression (LUR) to predict high spatial-resolved source contributions, and estimated the source-specific exposure and risk by personal activity time- and population-weighting.

Size distribution, meteorological influence and uncertainty for source-specific risks: PM and PM-bound PAHs and heavy metals in a Chinese megacity during 2011-2021.

This study aims at exploring size distribution, meteorological influence and uncertainty for source-specific risks of atmospheric particulate matter (PM), which can improve risk-mitigation strategies for health protection. Heavy metals (HMs) and polycyclic aromatic hydrocarbons (PAHs) in PM and PM were detected in a Chinese megacity during 2011-2021. A new method named as PMFBMR, which combines the Positive Matrix Factorization, Bootstrapping, Mote Carlo and Risk assessment model, was developed to estimate uncertainty of source-specific risks.

Seasonal variation and source apportionment of inorganic and organic components in PM: influence of organic markers application on PMF source apportionment.

PM samples collected over a 1-year period in a Chinese megacity were analyzed for organic carbon (OC), elemental carbon (EC), water-soluble ions, elements, and organic markers such as polycyclic aromatic hydrocarbons (PAHs), hopanes, steranes, and n-alkanes. To study the applicability of organic markers in source apportionment, the relationship between organic and inorganic components was analyzed, and four scenarios were implemented by incorporating different combinations of organic and inorganic tracers. The consistent temporal variations trend of 4-ring PAHs and SO prove that coal burning directly emits a portion of sulfate.

[Influence of Typical Desulfurization Process on Flue Gas Particulate Matter of Coal-fired Boilers].

As flue gas desulfurization (FGD) was one of the most important purification processes of coal-fired boilers, we selected four boilers, which were equipped with wet limestone, furnace calcium injection, ammonia-based, and double-alkali FGDs, to research the influence of FGDs on the flue particulate matter (PM). The flue PM before and after the FGD were sampled using laboratory resuspension and dilution tunnel sampling methods, respectively, and the PM was analyzed for its chemical composition (i.e.

Source-specific risks of synchronous heavy metals and PAHs in inhalable particles at different pollution levels: Variations and health risks during heavy pollution.

Synchronous heavy metals (HMs) and polycyclic aromatic hydrocarbons (PAHs) in inhalable particulate matter (PM) were measured during 2009-2012 and 2015-2016 in a Chinese megacity (Chengdu) to understand the variations in source-specific health risks during haze episodes. Samples were divided into four mass concentration levels: PM ≤ 150 μg m (L1), 150 μg m < PM ≤ 250 μg m (L2), 250 μg m < PM ≤ 350 μg m (L3), and PM > 350 μg m (L4). The percentages of some HMs and PAHs (accounting for PM) decreased from L1 to L4, indicating that they exhibited lower growth rates than other species during heavy pollution.

Comprehensive evaluation of flue gas desulfurization and denitrification technologies of six typical enterprises in Chengdu, China.

Post-combustion flue gas desulfurization and denitrification technologies are essential in achieving the full compliance of fine particulate matter (PM, aerodynamic diameter less than 2.5 μm) air quality standards by 2030 in China as sulfur dioxide (SO) and nitrogen oxides (NO) are the main precursors of PM. Some studies have addressed the performance evaluation of desulfurization technology, but none included the water-soluble ions (sulfate (SO), nitrate (NO), etc.

Prediction of Bronchopulmonary Dysplasia in Preterm Infants Using Postnatal Risk Factors.

To identify postnatal risk factors for bronchopulmonary dysplasia (BPD) development in preterm infants with gestational age ≤32 weeks. Seventy-two preterm infants(30 with BPD and 42 non-BPD controls) admitted in the neonatal intensive care unit (NICU) of the Children's Hospital of Soochow University during 2017 were enrolled in this prospective longitudinal study. Perinatal clinical data, a neonatal critical illness score (NCIS), different soluble B7-H3(sB7-H3), and interleukin-18 (IL-18) levels by days after birth were collected.

MicroRNA-107 promotes apoptosis of acute myelocytic leukemia cells by targeting RAD51.

Introduction: This study aimed to investigate the role of microRNA (miRNA) that affects acute myelocytic leukemia (AML) and its potential molecular mechanism by constructing a miRNA-mRNA interaction network using bioinformatics methods.

Material And Methods: MicroRNA expression data of AML were retrieved from Gene Expression Omnibus (GEO) and analyzed by microarray analysis. Expression levels of miR-107 and RAD51 mRNA were detected by quantitative real time polymerase chain reaction (qRT-PCR).

[Source Profiles of VOCs Associated with Typical Industrial Processes in Chengdu].

The characteristics of volatile organic compound (VOCs) species from various production procedures of wood-based panel production and other industrial processes in Chengdu were analyzed through gas chromatography-mass spectrometry (GC-MS) and other methods specified in national standards after the emissions of typical enterprises of wood-based panel production, pharmaceutical manufacturing, chemical production and other industrial processes in Chengdu had been sampled using sampling bottles and SUMMA canisters. Generally, the process of wood-based panel production includes glue making, glue mixing, sorting, and hot pressing, whereas the process of pharmaceutical manufacturing includes workshop production and wastewater treatment. The results showed that the main contribution species of VOCs in wood-based panel production and pharmaceutical manufacturing is oxygenated VOCs (OVOCs), accounting for more than 50% of the total VOCs emitted.

Comparative study of PM-bound heavy metals and PAHs during six years in a Chinese megacity: Compositions, sources, and source-specific risks.

To comparatively analyze source-specific risks of atmospheric particulate matter (PM), PM-bound polycyclic aromatic hydrocarbons (PAHs) and heavy metals (HMs) were synchronously detected in a megacity (Chengdu, China) from 2009 to 2016. Non-cancer risk (assessed by hazard quotient, HQ) of PAHs and HMs was within the acceptable level, while cancer risk (assessed by incremental life cancer risk (ILCR), R) of PAHs and HMs were 1.01 × 10 and 9.

[Speciated VOCs Emission Inventory and Ozone Formation Potential in Sichuan Province].

Based on the measured data in the literature, VOCs (volatile organic compounds) source profiles were revised and reconstructed without OVOCs (oxygenated volatile organic compounds) species to obtain the normalized VOCs source profiles. Using the 2015 Sichuan emission inventory, source profiles based on the 1 km×1 km gridded speciated VOCs emission inventory were developed, and the ozone formation potentials of the species were estimated to assess the environmental impact on ozone formation. The established VOCs source profile database consists of 45 source profiles and 519 species.

Comparative Transcriptome and iTRAQ Proteome Analyses Reveal the Mechanisms of Diapause in Ashmead (Hymenoptera: Aphidiidae).

Ashmead (Hymenoptera: Aphidiidae) is a solitary endoparasitoid used in the biological control of various aphids. Diapause plays an important role in the successful production and deployment of . Diapause can effectively extend the shelf life of biological control agents and solve several practical production problems like long production cycles, short retention periods, and discontinuities between supply and demand.

[X-Ray Fluorescence Intensity Calculation for Micro-Particles via MCNPX and WDXRF Experiment].

In order to research the effect of X-ray fluorescence (XRF) analysis on the results in the sample’s micro particles, MCNPX models had been established for an X-ray fluorescence analyzer in this paper. It had studied the characteristics of the samples with different particle sizes, the fluorescence peak counts, the peak to total ratios and the peak to source ratios. A micro particle analysis experiment had been designed for its verification.

[Effects of matrine on cgi-100 gene expression and proliferation in K562 cells].

This study was aimed to explore the expression level of the unknown cgi-100 gene in human leukemia K562 cells treated with matrine, and to investigate effect of cgi-100 on proliferation of K562 cells. The expression level of cgi-100 was detected by RT-PCR in K562 cells before and after being treated with matrine; pIRES2-EGFP/cgi-100 eukaryotic expression vector was constructed by DNA recombinant technique and was introduced into K562 cells by liposome-mediated DNA transfection. The cgi-100 gene expression level, growth-curve, and cell cycle of the modified K562-cgi-100 cells were detected by RT-PCR, Trypan blue staining and FCM.

[The expression of IER3IP1 gene in K562 cells treated by matrine and its effect on the cell growth].

Objectives: To investigate the expression status of IER3IP1 gene during matrine induced K562 cell differentiation, and to figure out the function of IER3IP1 gene in K562 cell line.

Methods: Trypan-blue staining was used to analyze the growth inhibitory effect of matrine on K562 cells. Semi-quantitative RT-PCR was employed to investigate the expression status of IER3IP1 gene treated with different time and dosage of matrine.