Isthmic spondylolisthesis combined with schwannoma occurring at the same vertebral level: a case report and literature review.

Background: The occurrence of schwannomas at the level of isthmic spondylolisthesis has not yet been reported. Preoperative identification of the responsible lesion and a rational surgical plan are essential for successful surgery.

Case Presentation: We report the case of a 56-year-old woman who presented with a six-year history of low back pain and a three-year history of radiating pain in the left lower extremity.

Natural polymer based drug-loaded hydrogel platform for comprehensive care of acute spinal cord injury.

Traumatic spinal cord injury typically occurs at significant depths and triggers rapid and severe physiological responses. It is commonly accompanied by oxidative stress disorders, lipid peroxidation, accumulation of toxic aldehydes, and edema among other symptoms. The management of this condition requires intricate surgical procedures and vigilance against postoperative complications.

Gluteus medius contracture: A case report and review of the literature.

Rationale: Bilateral gluteus medius contractures in adults are rare in clinical practice, with only a few cases reported. These contractures may result from repeated intramuscular injections during childhood. Understanding the clinical manifestations, diagnostic process, treatment, and outcomes can provide insights into effective management strategies.

Regulation of dynamic spatiotemporal inflammation by nanomaterials in spinal cord injury.

Spinal cord injury (SCI) is a common clinical condition of the central nervous system that can lead to sensory and motor impairment below the injury level or permanent loss of function in severe cases. Dynamic spatiotemporal neuroinflammation is vital to neurological recovery, which is collectively constituted by the dynamic changes in a series of inflammatory cells, including microglia, neutrophils, and astrocytes, among others. Immunomodulatory nanomaterials can readily improve the therapeutic effects and simultaneously overcome various drawbacks associated with treatment, such as the off-target side effects and loss of bioactivity of immune agents during circulation.