Construction of a combined prognostic model for pancreatic ductal adenocarcinoma based on deep learning and digital pathology images.

Background: Deep learning has made significant advancements in the field of digital pathology, and the integration of multiple models has further improved accuracy. In this study, we aimed to construct a combined prognostic model using deep learning-extracted features from digital pathology images of pancreatic ductal adenocarcinoma (PDAC) alongside clinical predictive indicators and to explore its prognostic value.

Methods: A retrospective analysis was conducted on 142 postoperative pathologically confirmed PDAC cases.

Gendered Parenting: Maternal Son Preference and Depressive Symptoms in Chinese Early Adolescents.

This study focused on the nuanced phenomenon of gendered parenting by exploring how maternal son preference is associated with depressive symptoms among Chinese early adolescents. Focusing on 1093 junior high school students from a relatively affluent city in Western China, this study examined the mediating roles of mother-child attachment and father-child attachment as well as the moderating role of school connectedness in the relationship between maternal son preference and depressive symptoms. The results revealed a noteworthy positive correlation between maternal son preference and depressive symptoms among female adolescents, with no significant association observed in males.

Nomogram incorporating prognostic immune-inflammatory-nutritional score for survival prediction in pancreatic cancer: a retrospective study.

Background: Prognosis prediction for pancreatic cancer has always been difficult in clinical practice because of its high heterogeneity and mortality. The aim of the study was to assess the value of prognostic immune-inflammatory-nutritional (PIIN) score on overall survival (OS) in postoperative patients with pancreatic cancer and to develop a nomogram incorporating PIIN score.

Methods: This study retrospectively analyzed the clinic pathological data of 155 patients with pancreatic cancer who underwent radical surgery.

The value of the preoperative Naples prognostic score in predicting prognosis in gallbladder cancer surgery patients.

Purpose: The Naples prognostic score (NPS) is a comprehensive prognostic model that includes inflammatory and nutrition-related indicators and is increasingly used as a prognostic score for various malignant tumors. Given its predictive effect on prognosis in patients with gallbladder cancer, it is currently unclear. This study aimed to investigate the role of preoperative NPS in predicting prognosis in gallbladder cancer surgery patients.

Machine learning-based nomogram for 30-day mortality prediction for patients with unresectable malignant biliary obstruction after ERCP with metal stent: a retrospective observational cohort study.

Background: This study aimed to investigate the risk factors for 30-day mortality in patients with malignant biliary obstruction (MBO) after endoscopic retrograde cholangiopancreatography (ERCP) with endobiliary metal stent placement. Furthermore, we aimed to construct and visualize a prediction model based on LASSO-logistic regression.

Methods: Data were collected from 245 patients who underwent their first ERCP with endobiliary metal stent placement for unresectable MBO between June 1, 2013, and August 31, 2021.

Psychological maltreatment and adolescent internet harassment perpetration: The mediating role of deviant peer affiliation and the moderating role of self-compassion.

Background: Psychological maltreatment has been regarded as a risk factor for adolescent internet harassment. However, previous studies failed to take family, peer, and individual factors into account comprehensively when comes to adolescent internet harassment perpetration.

Objective: Based on the Social-Ecological Diathesis-Stress Model, the present study established a moderated mediation model to investigate the mediating role of deviant peer affiliation in the association between psychological maltreatment and adolescent internet harassment perpetration, as well as the moderating role of self-compassion.

Nursing Method of Patients with Severe Traumatic Brain Injury and Fracture in the Ambulance.

Craniocerebral injury accounts for 9%-21% of the injuries in all parts of the body, and the incidence rate ranks first in all types of trauma or only lower than limb fractures. This study mainly discusses the nursing methods of patients with severe traumatic brain injury and fractures in ambulances. This study is based on risk factors with moderate-to-higher association strength from retrospective studies.

The Association between Coparenting Behavior and Internalizing/Externalizing Problems of Children and Adolescents: A Meta-Analysis.

This study aimed to determine the association between coparenting behavior and children's externalizing and internalizing problems and possible factors that may moderate their associations. A meta-analysis of 93 studies involving 41,207 participants found that coparenting behavior was slightly and significantly related to externalizing problems, r = -0.17, 95% CI [-0.

Prevalence of congenital heart disease among school children in Qinghai Province.

Objectives: This study aimed to investigate the prevalence of congenital heart disease (CHD) among school children in Qinghai province, a high-altitude region in China.

Methods: A cross-sectional study was conducted among school-aged children in 2019. All subjects completed a survey with a structure questionnaire and underwent CHD screening.

Childhood Psychological Maltreatment and Depression among Chinese Adolescents: Multiple Mediating Roles of Perceived Ostracism and Core Self-Evaluation.

Previous studies have primarily focused on the separate mediating role of interpersonal context or personal characteristics in the relationship between childhood psychological maltreatment and depression, neglecting the combined effects, which have limited ecological validity. Therefore, this study investigated the multiple mediating roles of perceived ostracism and core self-evaluation in the relationship between childhood psychological maltreatment and depression. A total of 1592 Chinese adolescents (51.

Prognostic Significance of Microvascular Invasion in Pancreatic Ductal Adenocarcinoma: A Systematic Review and Meta-Analysis.

BACKGROUND The incidence, pathogenesis, and prognostic effect of microvascular invasion on pancreatic ductal adenocarcinoma (PDAC) remain controversial. This study aimed to summarize the incidence, pathogenesis, role in clinical management, recurrence, and prognostic significance of microvascular invasion in PDAC. MATERIAL AND METHODS A literature review and meta-analysis were performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement.

Negative Emotions and Job Burnout in News Media Workers: A Moderated Mediation Model of Rumination and Empathy.

News media workers are in stressful and competitive professions susceptible to negative emotions. Although the relationship between negative emotions and job burnout has been evidenced in some professional fields, it has not yet been examined in the population of news media workers. Far few studies have revealed the mediating and moderating mechanism between negative emotions and job burnout.

Prognostic Impact of DHRS9 Overexpression in Pancreatic Cancer.

Purpose: Pancreatic cancer (PC) has poor prognosis despite systemic treatment. Dehydrogenase/reductase member 9 (DHRS9) has been reported to be involved in many events of tumorigenesis, but its prognostic impact in PC remains undetermined. Thus, this study aimed to explore the association between DHRS9 expression and the prognosis of PC and investigate the possible mechanism by which DHRS9 is involved in PC progression.

Negative emotions and quality of life among adolescents: A moderated mediation model.

Background/objective: Depression, anxiety and stress are known as negative emotions. Previous studies have shown that negative emotions were associated with quality of life. There are a lot of researches on quality of life.

Correction to: Parental Phubbing and Adolescents' Depressive Symptoms: Self-Esteem and Perceived Social Support as Moderators.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Difficulties in Emotion Regulation and Cyberbullying Among Chinese Adolescents: A Mediation Model of Loneliness and Depression.

Recent research has ascertained some risk factors for cyberbullying. However, few studies have investigated the potential influence of difficulties in emotion regulation (DER) on cyberbullying, and there is little knowledge about the mediating mechanisms underlying this association. This study investigated whether DER would be significantly related to adolescent cyberbullying and whether loneliness and depression would sequentially mediate the link between DER and adolescent cyberbullying.

Childhood Emotional Abuse and Depression Among Adolescents: Roles of Deviant Peer Affiliation and Gender.

Adolescent depression is a significant concern around the world. There is a pressing need to explore risk factors for this disorder to develop better interventions. Based on an integration of attachment theory, Bronfenbrenner's ecological systems theory, and relational theory, the current study aimed to examine (a) whether childhood emotional abuse (CEA) would be significantly and positively related to adolescents' depression, (b) whether deviant peer affiliation would mediate the relation between CEA and depression, and (c) whether gender would moderate the direct and indirect relations between CEA and adolescent's depression via deviant peer affiliation.

Childhood Maltreatment and Bullying Perpetration among Chinese Adolescents: A Moderated Mediation Model of Moral Disengagement and Trait Anger.

Background: Childhood maltreatment plays an important role in adolescents' bullying perpetration. However, the mediating and moderating mechanisms underlying this association remain largely unknown.

Objectives: The current study examined the relationship between childhood maltreatment and adolescents' bullying perpetration and extended previous literature by examining the mediating effect of moral disengagement and the moderating effect of trait anger in this relationship.

Childhood maltreatment and prosocial behavior among Chinese adolescents: Roles of empathy and gratitude.

Background: Childhood maltreatment, including both abuse (physical, emotional, and sexual) and neglect (physical and emotional), is especially detrimental to adolescent development. However, most studies have been conducted within a psychopathological framework and focused on its role in exacerbating negative outcomes. Its adverse effect on adolescents' positive functioning, including empathy, gratitude, and prosocial behavior, is relatively underexplored.

Parental Phubbing and Adolescents' Depressive Symptoms: Self-Esteem and Perceived Social Support as Moderators.

Parental phubbing refers to the extent to which parents use or are distracted by their cell phone when they interact with their children. There has been growing scholarly interest in understanding the adverse effects of parental phubbing on adolescents' development. However, it is less clear whether parental phubbing potentially increases adolescents' depressive symptoms, to date, and the understanding of the factors which may affect this relationship is also limited.

School Climate and Adolescents' Cyberbullying Perpetration: A Moderated Mediation Model of Moral Disengagement and Friends' Moral Identity.

Based on an integration of the positive youth development model and the social cognitive theory, friends' moral identity was examined as a moderator of the direct and indirect relations between school climate and adolescent's cyberbullying perpetration via moral disengagement. Participants were 404 Chinese adolescents ( = 13.53 years, = 0.