Publications by authors named "Fengqin He"

Despite the accuracy and robustness attained in the field of object tracking, algorithms based on Siamese neural networks often over-rely on information from the initial frame, neglecting necessary updates to the template; furthermore, in prolonged tracking situations, such methodologies encounter challenges in efficiently addressing issues such as complete occlusion or instances where the target exits the frame. To tackle these issues, this study enhances the SiamRPN algorithm by integrating the convolutional block attention module (CBAM), which enhances spatial channel attention. Additionally, it integrates the kernelized correlation filters (KCFs) for enhanced feature template representation.

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Developing an OER electrocatalyst that balances high performance with low cost is crucial for widely adopting PEM water electrolyzers. Ru-based catalysts are gaining attention for their cost-effectiveness and high activity, positioning them as promising alternatives to Ir-based catalysts. However, Ru-based catalysts can be prone to oxidation at high potentials, compromising their durability.

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Article Synopsis
  • * This study investigates the effects of trehalose, an autophagy inducer, on SCA3 by examining its impact on aggregate formation and cell viability in a specific cell model expressing ataxin-3 proteins with different polyQ lengths.
  • * Results show that trehalose reduces the formation of toxic protein aggregates and lowers ataxin-3 levels, indicating its potential as a neuroprotective treatment for SCA3, likely due to its antioxidant properties and ability to enhance autophagy
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Background: To determine the efficacy of music therapy on pain relief during fundus screening in infants.

Methods: The sample consisted of infants aged 0 to 3 months who required fundus screening. Infants were randomized to fast music, slow music, and control groups.

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The successful large-scale cultivation of morel mushrooms () requires a comprehensive understanding of the soil bacterial communities associated with morel-farming beds, as the interactions between fungi and bacteria play a crucial role in shaping the soil microbiome. In this study, we investigated the temporal distribution and ecological characteristics of soil bacteria associated with morel fruiting bodies at different stages, specifically the conidial and primordial stages, under two cropping regimes, non-continuous cropping (NCC) and continuous cropping (CC). Our findings revealed a significant reduction in the yield of morel primordia during the third year following 2 years of CC (0.

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Background: As an intestinal non-specific inflammatory lesion, ulcerative colitis (UC) affects the health of many individuals. This study examined the possible beneficial effects of the chloroform extract of (Swartz.: Fr) Karst (FPKc) on UC.

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During development, many aspects of behaviour, including partner preferences and sexual behaviour, are "organized" by neural aromatization of androgen and oestrogen. This study aimed to analyse these processes in the mandarin vole (Microtus mandarinus); this is a novel mammalian model exhibiting strong monogamous pair bonds. Male pups were treated daily with a sesame oil only (MC) or the oestrogen receptor blocker-clomiphene citrate sesame oil mixture (MT) from prenatal day 14 to postnatal day 10.

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Exercise can reduce the incidence of stress-related mental diseases, such as depression and anxiety. Control group was neither exposed to CVMS nor TRE (noCVMS/noTRE). Females were tested and levels of serum17-beta-oestradiol (E), estrogen receptors α immunoreactive neurons (ERα-IRs), estrogen receptors β immunoreactive neurons (ERβ-IRs) and oxytocin immunoreactive neurons (OT-IRs) were measured.

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The inorganic perovskite has a better stability than the hybrid halide perovskite, and at the same time it has the potential to achieve an excellent photoelectric performance as the organic-inorganic hybrid halide perovskite. Thus, the pursuit of a low-cost and high-performance inorganic perovskite solar cell (PSC) is becoming the research hot point in the research field of perovskite devices. In setting out to build vacuum-free and carbon-based all-inorganic PSCs with the traits of simple fabrication and low cost, we propose the ones with a simplified vertical structure of FTO/CsPbIBr/carbon upon interfacial modification with PEI species.

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Optical microcavity configuration is one optical strategy to enhance light trapping in devices using planar electrodes. In this work, the potential application of optical microcavity configuration with ultrathin metal electrodes in highly efficient perovskite solar cells (PSCs) was investigated. By comparing with the device with conventional indium-tin-oxide (ITO) electrodes, it is shown that by carefully designing the Ag/dielectric planar electrode, a device with an optical microcavity structure can achieve comparable-or even higher-power conversion efficiency than a conventional device.

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Article Synopsis
  • Estradiol plays a crucial role in organizing behaviors related to partner preferences and sexual conduct during the development of mandarin voles, a species known for strong monogamous pair bonds.
  • Female pups were treated with either β-Estradiol or an oil vehicle, while male pups received only the oil vehicle, leading to significant differences in partner preferences and sexual behaviors when tested at 3 months old.
  • The study found that females treated with estradiol exhibited greater expression of estrogen receptors in specific brain areas compared to males and control females, suggesting that perinatal estradiol treatment influences adult mating behavior and partner choices.
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Nuclear localization of ataxin-3 plays a fundamental role in seeding aggregation and the pathology of spinocerebellar ataxia type 3 (SCA3). However, very few compounds that are able to modulate the nuclear transport of ataxin-3 have been identified. In our previous study, we found that divalproex sodium (DVS) reduced heat shock-induced nuclear localization of ataxin-3.

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Oestrogen has both anxiogenic and anxiolytic effects because of variation in opposing action on alpha (ERα) and beta (ERβ) estrogen receptors in the medial preoptic area (mPOA), bed nucleus of the stria terminalis (BNST) and medial amygdala (MeA). Oxytocin (OT) reverses some of the anxiogenic effects of oestrogen in the hypothalamic paraventricular nucleus (PVN) and supraoptic nucleus (SON). Because anxiety disorders are twice as common in women as in men, and oestrogen and OT are more important in females, we examined interactions between prenatal restraint stress (GS) and postnatal early short-term maternal separation (MS) and female mandarin vole behaviour, estrogen receptors and OT.

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Although the effect of early social environments on maternal care in adulthood has been examined in detail, few studies have addressed the long-term effect on paternal care and its underlying neuroendocrine mechanisms. Here, using monogamous mandarin voles (Microtus mandarinus) that show high levels of paternal care, the effects of early bi-parental separation (EBPS) or neonatal paternal deprivation (NPD) on adult paternal behavior, serum corticosterone levels, and receptor mRNA expression in the nucleus accumbens (NAcc) and medial preoptic area (MPOA) were investigated. Compared to the parental care group (PC), we found that EBPS reduced crouching behavior and increased inactivity, self-grooming, and serum corticosterone levels in adult offspring; and NPD significantly reduced retrieval behavior and increased self-grooming behavior of offspring at adulthood.

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In monogamous mammals, fathers play an important role in the development of the brain and typical behavior in offspring, but the exact nature of this process is not well understood. In particular, little research has addressed whether the presence or absence of paternal care alters levels of hippocampal glucocorticoid receptor (GR) and brain-derived neurotrophic factor (BDNF), and basal levels of serum corticosterone (CORT) and adrenocorticotropin (ACTH). Here, we explored this concept using socially monogamous mandarin voles (Microtus mandarinus), a species in which fathers display high levels of paternal care toward their pups.

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In many rodent species, including mandarin voles (Microtus mandarinus), the behavioral response to odors is regulated by a network of steroid-sensitive ventral forebrain nuclei including the medial amygdala (Me), bed nucleus of the striaterminalis (BNST), and medial preoptic area (MPOA). Although it is well-known that Me, BNST, and MPOA are closely interconnected, function independently in regulating odor-guided social behaviors, little is known about how order information is processed in the sub-regions of Me, BNST, and MPOA. In order to answer this question, we let male mandarin voles expose to two different odors including female vaginal fluid (FVF) and male flank gland secretion (MFGS) and detect the expression of Fos, androgen receptor (AR) and testosterone (T) in the sub-regions of Me, BNST, and MPOA.

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Perinatal period and adolescence are critical for brain development, which is the biological basis of an individual's sexual orientation and sexual behavior. In this study, animals were divided into two groups and their sexual orientations were observed: one group experienced drug treatments during the perinatal period, and the other group was castrated at puberty. The results showed that estradiol treatment had no effect on mature male offspring's sexual orientations, but 9 days and 14 days of clomiphene citrate treatment significantly increased the chance of homosexuality and effeminized behavior.

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Androgen receptors participate in the neuroendocrine regulation of male sexual behavior, primarily in brain areas located in the limbic system. Males of many species present a long-term inhibition of sexual behavior after several ejaculations, known as sexual satiety. It has been shown in rats that androgen receptor expression is reduced 24h after a single ejaculation, or mating to satiety, in the medial preoptic area, nucleus accumbens and ventromedial hypothalamus.

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High levels of paternal care are important for the development of social behavior in monogamous rodents. However, the effects of paternal care on the formation of pair bonding and underlying neuroendocrine mechanisms, especially the involvements of dopamine system and corticosterone, are not well understood. We investigated effects of paternal deprivation on pair bonding in mandarin voles (Microtus mandarinus), a socially monogamous rodent.

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Aggression in socially monogamous mandarin vole (Microtus mandarinus) was observed after castration. Levels of serum sex hormones and their central receptors were also measured using enzyme-linked immunosorbent assay and immunohistochemistry methods. The data indicate that adult males showed higher levels of aggression after castration.

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Early deprivation is popularly used in rodent models as an early life social stress to investigate and determine the factors that affect the development of the brain and behavior. Ultrasonic calls made by pups play an important role in parental-pup interactions during the neonatal period. However, whether repeated early deprivation affects the properties of ultrasonic vocalizations (USVs) produced by mandarin vole (Microtus mandarinus) pups, and whether ontogenetic development is subsequently affected, remains unclear.

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Bisphenol A (BPA) is a widespread endocrine disrupting chemical that influences adult physiology and behavior after perinatal exposure. However, it is not clear if pubertal exposure to BPA exerts hormone dependent effects on behaviors. Using C57BL/6J mice, we sought to determine how pubertal exposure to BPA affects locomotion, exploration, anxiety and sociability in adulthood.

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Various hypotheses have been proposed to explain factors influencing male alloparental behavior in cooperatively breeding species. Mandarin voles (Microtus mandarinus) are ideal animal models to investigate these factors because they are highly social rodents and display biparental care and spontaneous parental care when exposed to foster pups. Here we test the idea that the sexual and paternal experience of males influences alloparental behavior toward novel pups, and that these experiences alter the expression of neuropeptide oxytocin (OT) and estrogen receptor alpha (ERalpha).

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