Publications by authors named "Fengliu Lu"
Article Synopsis
- Xanthanolides, or seco-guaianolides, are unique compounds known for their diverse biological activities and typically have a lactone ring structure known as a 12,8-olide.
- The study uncovered the complete biosynthetic pathway for 8-epi-xanthatin, revealing that its structure originates from germacrene A acid through an oxidative process guided by a special cytochrome P450 enzyme.
- This new understanding of xanthanolide biosynthesis contrasts with previous findings about 12,6-guaianolides and paves the way for using synthetic biology to produce xanthanolides in microbes.
