Publications by authors named "Fengli Si"

This study aimed to investigate the real-world standardisation and adherence of medical treatment regimens in patients with chronic obstructive pulmonary disease (COPD) in the community for making future management strategy. The follow-up data and treatment information of patients with COPD, which were collected through the Management Information Center of COPD (MICCOPD) in 21 community health service centres in Songjiang District, a countryside region of Shanghai. Concordance between the pharmaceutical treatment plan and recommendation of 2017 Global Initiative for Chronic Obstructive Lung Disease (GOLD) report during the follow-up management period, as well as the medication adherence by patients,were analysed.

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Purpose: Only limited studies have depicted the unique features and management of refractory chronic cough (RCC) and unexplained chronic cough (UCC). These led to the initiation of this study, which reported the demographic characteristics, manifestations, and long-term outcomes on a large series of consecutive RCC/UCC patients, providing a guideline-led real-world clinical experience.

Methods: Retrospective baseline information was obtained from Clinical Research Database (January 2016 to May 2021).

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Article Synopsis
  • The study focuses on the management of refractory chronic cough (RCC) and the effectiveness of various treatments used in a specialist cough clinic.
  • A total of 369 RCC patients were analyzed, with most having tried multiple neuromodulators; around 71.3% showed positive responses to at least one treatment.
  • The findings suggest that while neuromodulators like gabapentin, deanxit, and baclofen have similar efficacy rates, a significant proportion of patients experienced improvements or control of their cough over time, reinforcing the value of individualized treatment strategies.
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Objective: To evaluate the real-world situation for the management of chronic obstructive pulmonary disease (COPD) and poorly controlled disease risk factors in the Chinese community.

Methods: This retrospective multicentre study analysed data from COPDMICand MICHC in Shanghai Songjiang District, Shanghai, China. The differences in COPD Assessment Test (CAT), the modified Medical Research Council (mMRC) dyspnea scale, and the number of emergency cases, emergency visits, inpatient cases, and hospitalisations from January 2018 to December 2020 were analysed.

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Background: Therapeutic efficacy of baclofen is suboptimal in the treatment of refractory gastroesophageal reflux-induced chronic cough (GERC). The purpose of the study is to identify its therapeutic predictors in a prospective clinical study.

Methods: 138 patients with suspected refractory GERC were treated with baclofen.

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