Flow injection chemiluminescence detection and solvent extraction for human skin ointment dexamethasone acetate absorption analysis and the reaction mechanism study.

A flow-injection chemiluminescence (CL) method coupled with solvent extraction for the determination of dexamethasone acetate (DA) in ointment was presented in this paper. It was based on the enhancing effect of the studied drug on CL emission of luminol-K(3)Fe(CN)(6) system. This method has the advantages of simple sample treatment, cheap instrumentation and rapid detection.