Publications by authors named "Fengjiao Cao"
Background: The co-disease of depression and gout is becoming more common in the modern era. However, the relationship between the severity of depressive symptoms and gout prevalence and treatment rate was still unclear.
Objective: This study aimed to determine the relationship between the prevalence, treatment rate of gout, and the severity of depression in the United States.
Article Synopsis
- Chronic nonbacterial osteomyelitis (CNO) is an auto-inflammatory bone disease that can cause rapid scoliosis progression, as seen in a 9-year-old girl whose condition worsened significantly within two months.
- Diagnostic imaging indicated severe spinal involvement, including a flattened T8 vertebra and a 25° curve in her spine, leading to a diagnosis of CNO.
- Treatment using adalimumab and zoledronic acid effectively improved her scoliosis after 6 months, but did not prevent a compression fracture in the affected vertebra.
SAPHO syndrome complicated with relapsing polychondritis: A case report.
Int J Rheum Dis
October 2023
Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare chronic inflammatory disease. The main clinical manifestation of SAPHO syndrome is an osteoarthropathy with cutaneous involvement. Relapsing polychondritis (RP) characterized by chronic inflammation and cartilage degeneration is a rare systematic autoimmune disease.
View Article and Find Full Text PDFContext: Zhishi Rhubarb Soup (ZRS) is a traditional Chinese medicine formula used in the clinic to treat acute cerebral infarction (ACI) for many years. However, the exact mechanism of the treatment remains unclear.
Objective: This study elucidates the multitarget mechanisms underlying the effects of ZRS on ACI using network pharmacology analysis and verify its effect by performing animal experiments.
The antibiotic resistance (ARE) subfamily of ABC (ATP-binding cassette) proteins confers resistance to a variety of clinically important ribosome-targeting antibiotics and plays an important role in infections caused by pathogenic bacteria. However, inhibitors of ARE proteins have rarely been reported. Here, OptrA, a new member of the ARE proteins, was used to study inhibitors of these types of proteins.
View Article and Find Full Text PDFKaempferol Inhibits the Primary Attachment Phase of Biofilm Formation in .
Front Microbiol
November 2017
The ability to form biofilms on surfaces makes the main pathogenic factor in implanted medical device infections. The aim of this study was to discover a biofilm inhibitor distinct from the antibiotics used to prevent infections resulting from biofilms. Here, we describe kaempferol, a small molecule with anti-biofilm activity that specifically inhibited the formation of biofilms.
View Article and Find Full Text PDFArticle Synopsis
- * Aloe-emodin was found to impact S. aureus biofilm development without being bactericidal, specifically hindering the early stages of biofilm formation, including adhesion and growth.
- * Analyses showed that aloe-emodin reduces the extracellular protein and polysaccharide components of the biofilm, providing new insights for potential treatments against S. aureus infections.