Publications by authors named "Fenghao Dai"
A series of asymmetric azobenzenes have been synthesized by radical-addition/ring-opening cascade reactions from 2-indazole in the presence of PIFA and alcohols under blue light irradiation and nitrogen protection. Furthermore, a wide range of functional groups were tolerated and the corresponding products were obtained in 30% to 95% isolated yields. The protocol is characterized by its visible-light initiation, avoidance of metals and photocatalysts, mild reaction conditions, and may find potential use in materials science and medicinal chemistry.
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- Electron-rich and hindered aryl chlorides are difficult to work with in Suzuki-Miyaura cross-coupling (SMC) reactions, but a new catalytic system shows promise.
- The study introduces an efficient catalytic system using very small amounts of commercially available catalysts, allowing for high yields (up to 92%) even with challenging substrates.
- The research also investigates how different solvents affect the reactions and explores the mechanisms of by-product formation, emphasizing reduced costs and simpler processes from using trace catalysts.