Ferumoxytol of ultrahigh magnetization produced by hydrocooling and magnetically internal heating co-precipitation.

Ferumoxytol, which is originally intended for MRI and anemia treatment, is currently the only inorganic nanodrug approved by FDA for clinical application in vivo. Common ferumoxytol seems incapable of meeting the requirements for diverse applications. Thus, the development of a novel strategy based on co-precipitation to produce ferumoxytol with high quality is an imminent task.

Assembly-Induced Thermogenesis of Gold Nanoparticles in the Presence of Alternating Magnetic Field for Controllable Drug Release of Hydrogel.

Films of gold nanoparticles are easily fabricated by layer-by-layer assembly. With increasing number of layers a transition of the electric property from insulating to conducting can be achieved. This conductivity leads to controllable thermogenesis of the film, which can be employed for drug release of loaded hydrogels.

Orientation-Dependent Thermogenesis of Assembled Magnetic Nanoparticles in the Presence of an Alternating Magnetic Field.

Thanks to thermogenesis in the presence of an alternating magnetic field, magnetic nanoparticles could play a promising role in local heating in vivo. However, the flexible control of thermogenesis for the given nanomaterials remains challenging. Here, we propose that the thermogenesis of assembled magnetic nanoparticles can be controlled by orientation of the film relative to an external field.