Publications by authors named "Feng-wu Tang"
Background: Intractable postherpetic neuralgia (PHN) can be difficult to manage even with aggressive multimodal therapies. Patients who experience uncontrolled refractory cranial PHN despite conservative treatment may benefit from an intrathecal drug delivery system (IDDS). For craniofacial neuropathic pain, the traditional approach has been to place the intrathecal catheter tip below the level of the cranial nerve root entry zones, which may lead to insufficient analgesia.
View Article and Find Full Text PDF[Effects of sodium selenite on the cell growth inhibition and intracellular reactive oxygen species of human brain glioma stem cells].
Zhongguo Ying Yong Sheng Li Xue Za Zhi
January 2013
Mesenchymal stem cells (MSCs) have been successfully isolated from a broad range of adult, fetal, and other nonembryonic tissues. Fetal lung has been identified as a rich source of MSCs. However, the biological characteristics and differentiation potential of fetal lung MSCs remain to be explored.
View Article and Find Full Text PDF[Intra-bone marrow cavity transplantation of human umbilical cord blood mononuclear cells into NOD/SCID mice].
Zhonghua Xue Ye Xue Za Zhi
May 2005
Objective: To evaluate the hematopoietic reconstitution of implanted NOD/SCID mice, after intra-bone marrow cavity injection (iBM) of human umbilical cord blood (CB) mononuclear cells (MNCs).
Methods: 24 female NOD/SCID mice were divided into different MNCs dosage iBM groups (3 x 10(6), 1 x 10(7), 3 x 10(7) cells), tail vein intravenous injection (iTV) group (3 x 10(7) cells) and control group (iBM of medium only). CB MNCs sorted by Ficoll-Hypaque were transplanted into left tibia bone marrow cavity of 6- to 8-week-old NOD/SCID mice, which were anesthetized and sublethally irradiated (270 cGy (137)Cs-gamma irradiation).
Article Synopsis
- Fresh human umbilical cord blood mononuclear cells (CBMNCs) can grow into neural cells and help improve brain function in rodent models of neurological conditions.
- The study found that CBMNCs produce higher levels of certain neurotrophic factors compared to adult blood cells (PBMCs).
- Specifically, increased levels of brain-derived neurotrophic factor (BDNF) and neurotrophin-4/5 (NT4/5) were detected in the CBMNCs, suggesting these factors may play a key role in repairing brain damage in animals after CBMNC treatment.
[In vitro vasculogenesis and angiogenesis of mouse embryonic stem cells].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
February 2005
Objective: To explore an optional condition to induce mouse embryonic stem (ES) cells to differentiate into endothelial cells and to establish in vitro models of vasculogenesis and angiogenesis.
Methods: Mouse ES cells were cultured in differentiation medium containing a cocktail of vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), interleukin-6 (IL-6) and erythropoietin (EPO) in 1% methylcellulose to induce formation of embryoid bodies (EBs). At day 11, EBs were harvested and suspended in rat-tail collagen type I with the same cocktail of cytokines cultured for three additional days.