Borneol-Modified Schisandrin B Micelles Cross the Blood-Brain Barrier To Treat Alzheimer's Disease in Aged Mice.

Schisandrin B (Sch B) is a bioactive dibenzocyclooctadiene derizative that is prevalent in the fruit of . Numerous studies have demonstrated that Sch B has a neuroprotective action by reducing oxidative stress and effectively preventing inflammation. It follows that Sch B is a potential treatment for Alzheimer's disease (AD).

Photosynthetic System Based on a Polyoxometalate-Based Dehydrated Metal-Organic Framework for Nitrogen Fixation.

In nature, biological nitrogen fixation is accomplished through the π-back-bonding mechanism of nitrogenase, which poses significant challenges for mimic artificial systems, thanks to the activation barrier associated with the N≡N bond. Consequently, this motivates us to develop efficient and reusable photocatalysts for artificial nitrogen fixation under mild conditions. We employ a charge-assisted self-assembly process toward encapsulating one polyoxometalate (POM) within a dehydrated Zr-based metal-organic framework (d-UiO-66) exhibiting nitrogen photofixation activities, thereby constructing an enzyme-mimicking photocatalyst.

Density and row spacing of short-season cotton suitable for machine picking in the cotton region of Yellow River Basin.

To determine the suitable planting density and row spacing of short-season cotton suitable for machine picking in the Yellow River Basin of China, we conducted a two-year field experiment in Dezhou during 2018-2019. The experiment followed a split-plot design, with planting density (82500 plants·hm and 112500 plants·hm) as the main plots and row spacing (equal row spacing of 76 cm, wide-narrow row spacing of 66 cm+10 cm, equal row spacing of 60 cm) as the subplots. We examined the effects of planting density and row spacing on growth and development, canopy structure, seed cotton yield and fiber quality of short-season cotton.

Heteropoly Blue/Protonation-Defective Graphitic Carbon Nitride Heterojunction for the Photo-Driven Nitrogen Reduction Reaction.

The establishment of a heterojunction is a crucial strategy to design highly effective nonnoble metal nanocatalysts for the photocatalytic nitrogen reduction reaction (PNRR). Heteropoly blues (r-POMs) can act as electron-transfer mediators in PNRR, but its agglomeration limits the further promotion of PNRR productivity. In this work, we construct a protonation-modified surface of N-vacancy -CN (HV-CN), achieving the high dispersion of r-POMs via the surface modification strategy.

Astragaloside-IV regulates endoplasmic reticulum stress-mediated neuronal apoptosis in a murine model of Parkinson's disease via the lincRNA-p21/CHOP pathway.

Objectives: Astragaloside-IV (AS-IV) protects the nerve cells of Parkinson's disease (PD) from damage. Long non-coding RNA (lincRNA) has been found to be important for many diseases. Lincnra-p21 is abnormally expressed in PD.

Reduced State of the Graphene Oxide@Polyoxometalate Nanocatalyst Achieving High-Efficiency Nitrogen Fixation under Light Driving Conditions.

The nitrogen (N) reduction to generate ammonia (NH) is a prerequisite for inputting fixed nitrogen (N) into a global biogeochemical cycle. Developing highly efficient photocatalysts for N fixation under mild conditions is still a challenge. Herein, we first report three kinds of reduction states of graphene oxide (GO)@polyoxometalate (POM) composite nanomaterials, which have outstanding photocatalytic N fixation activities in pure water without any other electronic sacrificial agents and cocatalysts at atmospheric pressure and room temperature.

Abiotic and biotic controls on dynamics of labile phosphorus fractions in calcareous soils under agricultural cultivation.

Soil labile inorganic and organic phosphorus (L-Pi and L-Po) extracted by NaHCO are potentially important sources of plant-available P. Their availability is strongly affected by soil physiochemical and biological properties. Here we conducted a field study in an arid region of northwestern China to investigate how L-Pi and L-Po dynamics are affected by changes in physiochemical and biological variables caused by agricultural cultivation of calcareous soils.

Association of five SNPs at the PARK16 locus as a susceptibility locus with Parkinson's disease for forensic application.

To investigate the association of five SNPs (rs823083, rs708723, rs4951261, rs823076 and rs16856110) at the PARK16 locus with Parkinson's disease (PD), and to potentiate its forensic application. The genomic DNAs of 215 PD patients and 212 matched controls from the northern Han Chinese population were amplified in two independent PCR systems and subsequently genotyped by digestion with the three endonucleases (Hinf I, Nco I and Msp I ). The genetic parameters and association studies were carried out with SPSS 13.

[Influence of soil salinization on soil animal community in an arid oasis of middle Heihe River basin].

An investigation was conducted on the status of soil salinization and the structure of soil animal community across six land use/cover types in an arid oasis of middle Heihe River basin, and the methods of redundancy analysis, regression analysis, and path analysis were adopted to analyze the responses of the soil animal community under different land use/cover types and different management modes to the various status of soil salinization. The six land use/cover types were 21-year old shrub land without irrigation and fertilization, 28-year old poplar and 33-year-old pine plantations with irrigation, 27- and 100-year-old farmlands with irrigation and fertilization, and natural grassland, from which all the other five land use/cover types were converted. The results demonstrated that land cover change in the absence of management practices did not lead to a significant change in the abundance and group richness of the soil animal community, while land cover change in the presence of management practices resulted in a significant change in the soil animal community.

[Distribution specificity of human fucosyltransferase 5 and its expression and localization in spermatids].

Objective: To investigate distribution specificity of human fucosyltransferase 5 (FUT5) as well as its expression and localization in spermatids.

Methods: Human semen, vaginal swab, saliva and venous blood from healthy individuals were collected. The spermatids were isolated and the spermatid membrane protein was then extracted.

Lack of association between three single nucleotide polymorphisms in the PARK9, PARK15, and BST1 genes and Parkinson's disease in the northern Han Chinese population.

Background: Parkinson's disease (PD) is an autosomally inherited neurodegenerative disease in elderly people. The etiology of PD has long been thought to be associated with both genetic and environmental factors. To explore potential genetic risk factors for PD in the northern Han Chinese population, we investigated three single nucleotide polymorphisms (SNPs) (rs4538475, rs11107 and rs12564040) in the BST1, PARK15 and PARK9 genes.

[The genetic diversity in the full coding region of human FUT5 gene in a Chinese Han population].

Objective: To reveal the sequence variations of the full coding region of the human alpha (1,beta/1,4) fucosyltransferase 5 gene (FUT5) in a Chinese Han population.

Methods: The whole coding region of the FUT5 gene was amplified and sequenced in a total of 30 unrelated Chinese Han individuals. The PCR products containing the nucleotide variants observed in the study were subcloned into plasmid pcDNA to determine all potential haplotypes in the investigated population.

[Effects of different irrigation and nitrogen supply levels on nitrate-N dynamics in a recently reclaimed sandy farmland in Heihe River basin].

Improper nitrogen (N) and irrigation management are major causes leading to deterioration in water environmental quality in the middle reaches of Heihe River basin. A controlled experimental study of different irrigation and N supply levels was therefore conducted in the Linze Inland River Basin Research Station, Chinese Academy of Sciences, to determine the influences of N addition and irrigation regime on the dynamics of nitrate-N (NO3(-) -N) distribution in soil profiles over the growing season of spring wheat. The experiment employed a completely randomized block split-plot design, with irrigation treatments [0.

[Dynamics of soil water under Eucommia ulmodes plantation in hilly red soil region of southern China].

By using time domain reflectometry (TDR), a fixed-position monitoring research on the dynamics of soil water under Eucommia ulmoides plantation was conducted in a hilly red soil region of southern China. The results showed that there was a significant difference in the soil water storage among different months, and the dynamics of soil water could be divided into the phases of reduction, increase, and more reduction. Soil water varied significantly in its vertical distribution, and the variation pattern also differed with seasons.

The relative importance of pre- and post-germination determinants for recruitment of an annual plant community on moving sandy land.

Background And Aims: The relative importance of pre- and post-germination determinants for recruitment of natural plant communities is rarely explored. An annual plant community on moving sandy land was chosen for a case study. Answers to the following questions were sought: (a) Does recruitment of new individuals within the community of annual plants differ in time and space? (b) Is there spatial concordance between seed deposition, seedling emergence, survival and recruitment? (c) What are the direct and indirect effects of pre- and post-germination determinants on plant recruitment.

Wind-dispersed seed deposition patterns and seedling recruitment of Artemisia halodendron in a moving sandy land.

Background And Aims: Artemisia halodendron is a native sub-shrub that occurs mainly in moving and semi-fixed sandy lands in Inner Mongolia, China. Information on the spatial patterns of wind-dispersed seed deposition and seedling recruitment of A. halodendron inhabiting moving sandy lands is very limited.

[Field investigation on ecological effect of windbreak and soil erosion reduction from sandy grasslands].

Through field observation of the variation of vegetational characteristics and sand transported rate in sandy grasslands at different levels of desertification during the spring erosive period, the ecological effects of windbreak and soil erosion reduction from sandy grasslands of the Horqin Sandy Land were studied. The results showed that vegetational coverage varied obviously from 0.3% in the shifting sand land of the severe desertification to 16% in the fixed sand land of the least desertification in mid May.