Publications by authors named "Feng-Zhi Chen"

Article Synopsis
  • Stem cell therapy shows promise for treating erectile dysfunction (ED), but understanding how transplanted stem cells function is still a work in progress.
  • This study investigated how modifying the myocardin gene could enhance the effectiveness and longevity of adipose-derived stem cells (ASCs) in improving erectile function using tests on rats.
  • Results indicated that while myocardin modification did not affect ASC apoptosis, it did reduce cell growth and boost contraction, ultimately improving the erectile function measurements and confirming the retention of ASCs in the tissue over time.
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Stem cell transplantation and low-energy shock-wave therapy (LESWT) have emerged as potential and effective treatment protocols for diabetic erectile dysfunction. During the tracking of transplanted stem cells in diabetic erectile dysfunction models, the number of visible stem cells was rather low and decreased quickly. LESWT could recruit endogenous stem cells to the cavernous body and improve the microenvironment in diabetic cavernous tissue.

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Objective: To investigate whether phenotypic modulation of bladder smooth muscle occurs in diabetic rats.

Methods: Thirty-two male SD rats were randomly assigned into diabetic group and control group. Diabetic rat models were established by a single intraperitoneal injection of streptozotocin (60 mg/kg).

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Objective: To evaluate the effects and safety of transperitoneal laparoscopic radical prostatectomy (TLRP) and extraperitoneal laparoscopic radical prostatectomy (ELRP) in the treatment of localized prostate cancer.

Methods: We searched the Cochrane Library, Medline, Chinese Journal Full-text Database, Wanfang and CBM for clinical controlled trials addressing TLRP and ELRP in the treatment of localized prostate cancer. Two independent reviewers extracted comparable data from eligible studies and performed meta-analysis with the Statal 2.

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