Publications by authors named "Feng-Yun Zhou"
Article Synopsis
- The study aimed to explore muscle differences in children with osteogenesis imperfecta (OI) using low-dose chest CT and to evaluate different muscle segmentation methods.
- The research involved analyzing CT images of 20 children with OI and 40 controls, measuring muscle size and density at specified spinal levels using two methods.
- Results showed that OI children had significantly lower muscle density compared to controls, suggesting that OI may affect muscle quality, and indicated that one segmentation method might not be ideal for this demographic.
The aim of this study was to construct a ribosome display library of single chain variable fragments (scFvs) associated with hepatocarcinoma and screen such a library for hepatocarcinoma-binding scFvs. mRNA was isolated from the spleens of mice immunized with hepatocellular carcinoma cell line HepG2. Heavy and k chain genes (VH and k) were amplified separately by RT-PCR, and an anti-HepG2 VH/k chain ribosome display library was constructed by assembling VH and k into the VH/k chain with a specially constructed linker by SOE-PCR.
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