Publications by authors named "Feng-Yun Shen"
[Simultaneous determination of 9 major components of dachengqi tang in rat plasma by UPLC-MS/MS].
Zhongguo Zhong Yao Za Zhi
June 2014
Article Synopsis
- A UPLC-MS/MS method was developed for the simultaneous measurement of nine key bioactive compounds in Dachengqi Tang within rat plasma.
- The method involved using an Aglient C18 column and a specific mobile phase combination, followed by exploring various plasma pre-treatment processes for effective extraction of the compounds.
- Results showed good linearity for the compounds, with extraction recoveries exceeding 69.39%, indicating that this method can support pharmacokinetic studies of Dachengqi Tang in rats.
Objective: The traditional decoction method of Dachengqi Tang is that "First boiling Magnolia officinalis and Citrus aurantium with a pipeful of water, taking out five litres from the decoction, removing residues, adding rheum officinale, boiling again, taking out two litres from it, removing residues, adding mirabilite, boiling it with low fire". According to it, residues of M. officinalis and C.
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