Publications by authors named "Feng-Yun Bai"
Article Synopsis
- Huachansu Capsule (HCSc), derived from the skin of dried toads, is traditionally used to treat malignant tumors but is associated with cardiotoxicity, the mechanisms of which remain unclear.
- The study aimed to identify the cardiotoxic effects of high-dose HCSc and investigate the underlying mechanisms using advanced techniques like UPLC-MS, toxicity experiments, and molecular analysis.
- Results indicated that specific components in HCSc could cause cardiac toxicity by affecting heart-related gene regulation and activating the cAMP signaling pathway, especially at higher doses.
Medical abortion is a common medical procedure that women choose to terminate an unwanted pregnancy, but it often brings post-abortion complications. Danggui (Angelica sinensis Radix)-Yimucao (Leonuri Herba), as a herbal pair (DY) in clinical prescriptions of traditional Chinese medicine, is often used in the treatment of gynecological diseases and has the traditional functions of tonifying the blood, promoting blood circulation, removing blood stasis and regulating menstruation. In this study, serum lipidomics were adopted to dissect the mechanism of DY in promoting recovery after medical abortion.
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