Publications by authors named "Feng-Quan Li"

Article Synopsis
  • Respiratory syncytial virus (RSV) has seen a surge in cases among children following the relaxation of COVID-19 restrictions, prompting a study in Yunnan, China to assess differences in RSV infection characteristics pre- and post-COVID-19.
  • The research included 2553 pediatric patients, analyzing various data, including demographics and clinical symptoms to identify factors associated with severe lower respiratory tract infection (SLRTI) across the two periods.
  • Findings revealed a shift in RSV seasonal patterns and an increase in severe cases, older patient age, and higher clinical and laboratory indicators in post-COVID-19 children compared to those admitted before the pandemic.
View Article and Find Full Text PDF

A short and practical synthesis of oseltamivir was accomplished in 11 steps from inexpensive and abundant diethyl D-tartrate starting material. This azide-free route featured an asymmetric aza-Henry reaction and a domino nitro-Michael/Horner-Wadsworth-Emmons (HWE) reaction as the key steps to construct the relevant cyclohexene ring of the product, which provided an economical and practical alternative for the synthesis of oseltamivir.

View Article and Find Full Text PDF