[Effect of overdose fluoride on the expression of enamelin in rat mandibular incisor].

Objective: To observe the effect of overdose fluoride on the expression of enamelin in rat mandibular incisor.

Methods: Twenty Wistar rats were divided randomly into two groups. Animals were maintained in standard environment with free access to food and distilled water (control group) or water added with 100 mg/L F-(experimental group).

[Effects of overdosed fluoride on rat's incisor expression of matrixmetalloproteinase-20 and tissue inhibitors of metalloproteinase-2].

Objective: To investigate the effects of overdosed fluoride on the expression of MMP-20 and TIMP-2 in rat incisor.

Methods: 20 Wistar rats were randomly divided into experiment group and control group. The distilled water was given in control group.

[Effect of overdose fluoride on expression of bone sialoprotein in developing dental tissues of rats].

Purpose: To investigate the changes of bone sialoprotein (BSP) in developing dental tissues of rats exposed to fluoride.

Methods: Twenty rats were randomly divided into two groups, one was with distilled water (control group), the other was with distilled water treated by fluoride (experimental group). When the fluorosis model was established, the changes of the expression of BSP were investigated and compared between the two groups.