Disseminated tumor cells homing into rats' liver: a new possible mechanism of HCC recurrence.

Aim: To detect the origin of hepatocellular carcinoma (HCC) recurring and attempt to propose a new recurrent mechanism.

Methods: Orthotopic liver allotransplantation was performed on male rats with HCC- induced by diethylnitrosamine using female donors. Metastatic tumors in transplanted livers were obtained.