Publications by authors named "Feng-Li Xu"

Article Synopsis
  • * After an emergency cesarean section, the male newborn exhibited respiratory distress and low oxygen levels, leading to immediate transfer to the cardiac intensive care unit.
  • * The mother was diagnosed with Marfan syndrome based on the cardiovascular and genetic findings, but she unfortunately died from cardiac arrest after surgery; this case indicates that severe heart problems can arise from Marfan syndrome even in fetuses.
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Sorafenib, a first-line drug for advanced hepatocellular carcinoma (HCC), shows a favorable anti-tumor effect while resistance is a barrier impeding patients from benefiting from it. Thus, more efforts are needed to lift this restriction. Herein, we first find that solute carrier family 27 member 5 (SLC27A5/FATP5), an enzyme involved in the metabolism of fatty acid and bile acid, is downregulated in sorafenib-resistant HCC.

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Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The Spike protein that mediates coronavirus entry into host cells is a major target for COVID-19 vaccines and antibody therapeutics. However, multiple variants of SARS-CoV-2 have emerged, which may potentially compromise vaccine effectiveness.

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