[Analysis of surface enhanced Raman scattering spectra of oxyhemoglobin for liver cancer with combined multivariate statistics].

Investigation of surface-enhanced Raman spectra of oxyhemoglobin for 30 liver cancers and 30 normal persons based on the silver nanofilm was reported. Principal components analysis (PCA) and independent variable T test were employed to develop effective diagnostic algorithms for distinguishing liver cancer form normal. Discriminant analysis was used to evaluate the diagnostic efficiency and the result indicates that SERS spectra of the oxyhemoglobin are obviously different between normal persons and liver cancers.