Publications by authors named "Feng-Fan Wang"
Deletion of the PPARδ gene exacerbates high-fat diet-induced nonalcoholic fatty liver disease in mice through the gut-liver axis.
Cell Mol Biol (Noisy-le-grand)
October 2023
Article Synopsis
- Gut microbiota dysbiosis significantly contributes to non-alcoholic fatty liver disease (NAFLD), with the gut-liver axis being pivotal in this process.
- The study investigated the impact of deleting the PPARδ gene on gut microbiota and NAFLD in mice on high-fat and normal diets, revealing that PPARδ deletion worsened liver inflammation and gut barrier health.
- Results showed that PPARδ-/- mice had reduced beneficial bacteria and increased harmful bacteria, linking these changes to the severity of NAFLD and associated metabolic and inflammatory indicators.
A giant and extensive solitary Peutz-Jeghers-type polyp in the antrum of stomach: Case report.
Medicine (Baltimore)
December 2017
Rationale: A solitary Peutz-Jeghers-type polyp is a hamartomatous polyp which without either mucocutaneous pigmentation or a family history of Peutz-Jeghers syndrome (PJS). It can occur in all of the gastrointestinal tract, but it is extremely rare in the stomach.
Patient Concerns: A 53-year-old man was admitted to the local hospital with left upper abdominal pain lasting 2 weeks.