The prognostic role of disseminated tumor cells detected in peripheral blood and bone marrow of colorectal cancer.

Background/aims: Disseminated tumor cells (DTCs) have been associated with clinical outcome in various malignancies. The aim of this study is to examine the status of DTC in peripheral blood (PB) and bone marrow (BM) of colorectal cancer (CRC) and to evaluate its clinical significance.

Methodology: A total of 75 CRC patients treated with radical resection were enrolled in this study.

[Nuclear factor-kappaB expression in peripheral blood polymorphonuclear leukocytes of patients with acute pancreatitis and the preventive effectiveness of pyrrolidine dithiocarbamate on NF-kappaB in vitro].

Objective: To investigate the expression of NF-kappaB in peripheral blood polymorphonuclear leukocyte (PMN) of acute pancreatitis (AP) and to assess the preventive effectiveness of pyrrolidine dithiocarbamate (PDTC) on NF-kappaB in vitro.

Methods: Nineteen patients and 16 healthy individuals as control were enrolled in this study. The expression of NF-kappaB in PMNs was determined by gel electrophoretic mobility shift assay (EMSA).