Impact of Breastfeeding Practices on Autistic Traits in Chinese Children Aged from 3 to 4 Years: Cross-Sectional Study.

: Although breastfeeding has been extensively documented to confer health benefits to infants in the early stages of their lives, the sustained influence that it has on autistic traits throughout childhood remains unclear. This study endeavors to explore the correlation between the length of exclusive breastfeeding, the overall duration of breastfeeding, and the manifestation of autistic traits in Chinese children. : A cross-sectional study was conducted among 17,382 three-year-olds residing in Longhua District, Shenzhen, China.

Advances in risk prediction models for cancer-related cognitive impairment.

Cancer-related cognitive impairment (CRCI) has emerged as a significant long-term complication in cancer survivors, particularly those undergoing chemotherapy, radiotherapy, or targeted therapies. Despite advances in treatment, CRCI affects patients' quality of life, impacting their daily functioning, work capacity, and psychological well-being. In recent years, research has focused on identifying predictive factors for CRCI and developing risk prediction models to facilitate early intervention.

Comparison of different approaches applied for surgical correction of partial anomalous pulmonary venous connection.

Background: Right anterolateral thoracotomy or left anterolateral thoracotomy applied to partial anomalous pulmonary venous connection correction have been reported to obtain cosmetic and less invasive outcomes as alternative approaches to median sternotomy. However, the application of different approaches is still confusing. We compared the perioperative and mid-term outcomes to seek indications of different approaches and guide surgical treatment of partial anomalous pulmonary venous connection.

Regulation of CRISPR trans-cleavage activity by an overhanging activator.

The clustered regularly interspaced short palindromic repeats (CRISPR)/Cas12a system exhibits extraordinary capability in the field of molecular diagnosis and biosensing, attributed to its trans-cleavage ability. The precise modulation of performance has emerged as a significant challenge in advancing CRISPR technology to the next stage of development. Herein, we reported a CRISPR/Cas12a regulation strategy based on an overhanging activator.

Synergies of air pollution control policies: A review.

Air pollution control necessitates the implementation of multiple policy instruments in a coordinated manner. However, the enforcement of different policy combinations may generate complementary or offsetting synergistic effects, thereby influencing policy effectiveness. Nevertheless, the direction of synergy and the mechanisms of action among heterogeneous policies is undefined in existing academic research.

Association between weekend catch-up sleep and hypertension of the United States population from 2017 to 2020: a cross-sectional study.

Background: Hypertension is a prevalent cardiovascular risk factor that significantly contributes to morbidity and mortality worldwide. Previous studies have highlighted the role of inadequate sleep during weekdays in the development of hypertension. However, the potential mitigative effects of weekend catch-up sleep (WCS) on hypertension have been less explored.

Associations of waist circumference and BMI with the trajectory of cardiometabolic multimorbidity in hypertensive patients: A multi-state model.

Background And Aims: The burden of cardiometabolic multimorbidity (CMM) in hypertensive patients is substantial, and obesity may play an important role in progression of CMM. We aim to explore associations of obesity with the transition patterns from hypertension to first cardiometabolic disease (FCMD), CMM, and death.

Methods And Results: 21 286 hypertensive patients over 40 were enrolled in Yinzhou Health Information System from 2010 to 2015, followed until June 30, 2022.

[Risk prediction of Reduning Injection batches by near-infrared spectroscopy combined with multiple machine learning algorithms].

In this paper, near-infrared spectroscopy(NIRS) was employed to analyze 129 batches of commercial products of Reduning Injection. The batch reporting rate was estimated according to the report of Reduning Injection in the direct adverse drug reaction(ADR) reporting system of the drug marketing authorization holder of the Center for Drug Reevaluation of the National Medical Products Administration(National Center for ADR Monitoring) from August 2021 to August 2022. According to the batch reporting rate, the samples of Reduning Injection were classified into those with potential risks and those being safe.

Comparison of bullying victimization and depression symptoms among Chinese adolescents before and after the end of the dynamic zero-COVID-19 policy: a repeated cross-sectional study.

Background: The COVID-19 pandemic has had a significant impact on the physical and mental health of human beings. Most adolescents in mainland of China have been infected with COVID-19 after the adjustment of the dynamic zero-COVID-19 policy. This study aims to analyze the relationship between the COVID-19 pandemic effect and depressive symptoms among adolescents in mainland China.

A three-dimensional marine plastic litter real-time detection embedded system based on deep learning.

Marine plastic pollution has emerged as a significant ecological and biological issue impacting global marine ecosystems. To develop real-time cleaning systems for marine plastic litter, we implemented a three-dimensional marine plastic litter real-time detection (3D-MPLRD) system that incorporates deep learning techniques. Specifically, image quality assessment and enhancement are applied to mitigate the adverse effects of harsh underwater conditions on image quality, thereby enhancing the training efficacy of models beyond that achieved by conventional approaches.

Difference of SARS-CoV-2 infection and influence factors between people with and without HIV infection.

Background: There are mixed findings in the literature regarding the association between HIV status and the risk of COVID-19 infection. Thus, we aimed to estimate the association between characteristics of HIV infection and the risk of COVID-19 Infection in a Chinese sample.

Methods: We conducted a cross-sectional survey of 1995 people living with HIV (PLWH) and 3503 HIV-negative adults in Ningbo, China.

Logical Analysis of Multiple miRNAs with Isothermal Molecular Classifiers Based on LATE-RCA.

Logical analysis of multiple-miRNA expression information and immediate output of diagnostic results facilitates early cancer detection. In this work, we constructed an isothermal molecular classifier capable of performing computations on multiple miRNAs and directly providing diagnosis results. First, we developed linear-after-the-exponential rolling circle amplification (LATE-RCA), a nearly linear isothermal amplification that does not destroy the original quantitative information about miRNAs.

Development and Evaluation of a Hypertension Prediction Model for Community-Based Screening of Sleep-Disordered Breathing.

Purpose: Approximately 30% of patients with sleep-disordered breathing (SDB) present with masked hypertension, primarily characterized by elevated nighttime blood pressure. This study aimed to develop a hypertension prediction model tailored for primary care physicians, utilizing simple, readily available predictors derived from type IV sleep monitoring devices.

Patients And Methods: Participants were recruited from communities in Guangdong Province, China, between April and May 2021.

Engineering thermostable fluorescent DNA aptamer for the isothermal amplification of nucleic acids.

Isothermal amplification-based nucleic acid detection technologies have become rapid and efficient tools for molecular diagnostics. Sequence-specific monitoring methods are crucial for isothermal amplification, as they help identify the occurrence of extended primer dimers, which can lead to false positive results. Fluorescent aptamers are promising tools for real-time monitoring of isothermal amplification but are inherently limited by thermostability.

A nomogram for predicting neonatal acute respiratory distress syndrome in patients with neonatal pneumonia after 34 weeks of gestation.

Objective: To establish a prediction nomogram for early prediction of neonatal acute respiratory distress syndrome (NARDS).

Methods: This is a retrospective cross-sectional study conducted between January 2021 and December 2023. Clinical characteristics and laboratory results of cases with neonatal pneumonia were compared in terms of presence of NARDS diagnosis based on the Montreux Definition.

CO2 field-flooding devices offer potential value for cardiopulmonary bypass procedures for CHD performed via a right-side small incision approach.

Objective: This study sought to evaluate the value of a CO field-flooding device in cardiopulmonary bypass (CPB) surgical procedures for congenital heart disease (CHD) performed via a right-side small incision approach.

Methods: Between April 2022 and December 2023, 234 children with simple CHD who underwent CPB via a right-side small incision approach were separated into a control group (n = 93) without the use of a CO field-flooding device and a treatment group (n = 141) in which this device was added to the traditional surgical manual exhaust. Demographic, perioperative, arterial blood gas (ABG), and laboratory test data were then compared between these groups of patients.

Association between weekday sleep, weekday-weekend sleep duration gap, and hypertension in American adolescents: a nationwide cross-sectional study.

Background: The increasing prevalence of primary hypertension among children and adolescents is a global health concern, with inadequate sleep duration identified as a significant risk factor. This study investigates the impact of weekday-weekend sleep duration gap (WWSDG) on hypertension among American adolescents.

Methods: Using data from the NHANES 2017-2020 cohort, we analyzed sleep patterns and hypertension prevalence among 430 adolescents.

Surgical treatment experience of seven cases of Berry syndrome.

Objective: Berry syndrome is a group of rare congenital cardiac malformations including aortopulmonary window (APW), aortic origin of the right pulmonary artery (AORPA), interruption of the aortic arch (IAA), patent ductus arteriosus (PDA) (supplying the descending aorta) and intact ventricular septum. This paper will analyze the clinical data of 7 patients with Berry syndrome who underwent surgical treatment in our institution and discuss the one-stage surgical correction of Berry syndrome in combination with the literature.

Methods: From January 2013 to July 2024, a total of 7 children with Berry syndrome were admitted to the Cardiac Surgery Department of Beijing Children's Hospital.

Interaction between walkability and fine particulate matter on ischemic heart disease: A prospective cohort study in China.

Background: Previous studies have suggested that neighborhoods characterized by higher walkability are related to a reduced risk of ischemic heart disease (IHD), whereas exposure to PM is positively associated with risk of IHD. Nevertheless, their joint impact on IHD warrants further investigation.

Methods: This prospective cohort study was performed in Yinzhou, Ningbo, China, comprising 47,516 participants.

Synergistic effects of air pollution control policies: Evidence from China.

To control severe air pollution, multiple policies have been adopted in China. However, the combined effect of these policies on reducing air pollution remains uncertain. By systematically evaluating the complementary and substitution effects of policy combinations across different regions, this study aims to identify the optimal combinations of multiple air pollution control policies and to explore the mechanisms of policy synergy, maximizing improvements in air quality.

Association Between Albumin Levels and Neonatal Acute Respiratory Distress Syndrome in Newborn Pneumoniae.

Objective: This study aims to investigate the relationship between serum albumin levels and neonatal acute respiratory distress syndrome (NARDS) in patients with newborn pneumonia, providing new insights for clinical interventions targeting NARDS.

Methods: A retrospective analysis of medical records of neonatal pneumonia patients admitted to the neonatal intensive care unit (NICU) at a tertiary medical institution from January 2021 to December 2023 was conducted. Patients were stratified based on hypoalbuminemia (defined as serum albumin levels < 35 g/L), clinical thresholds, and albumin level quartiles.

Evaluating the relationship between obstructive sleep apnea and all-cause and cause-specific mortality in adults with and without metabolic syndrome using real-world data.

Background And Aim: Obstructive Sleep Apnea (OSA) is a prevalent sleep disorder linked to increased risks of cardiovascular and metabolic disorders, significantly raising overall mortality rates. This study explores the associations between OSA and mortality in adults with and without Metabolic Syndrome (MetS) using data from the National Health and Nutrition Examination Survey (NHANES).

Methods And Results: Data from NHANES (2005-2008) were analyzed, including 11,759 participants.

Significance of respiratory virus coinfection in children with Mycoplasma pneumoniae pneumonia.

Objective: Mycoplasma pneumoniae is a major causative pathogen in community-acquired pneumonia. Respiratory viral coinfections in children with Mycoplasma pneumoniae pneumonia (MPP) are not uncommon and cause severe clinical manifestations. This study aims to investigate the impacts of viral coinfection in MPP patients and hopes to offer novel insights for discriminating between MPP and MPP coinfection.