Publications by authors named "Feng Rong"

Background: Esophageal cancer (EC) often occurs in the elderly, with approximately 33% of patients aged ≥ 75 years at the time of diagnosis.

Aim: To evaluate the prognostic factors for radiotherapy (RT) in elderly patients with unresectable EC.

Methods: We retrospectively analyzed the clinical characteristics, toxic reactions, and survival information of EC patients aged ≥ 75 years who underwent intensity-modulated RT at Lu'an Hospital of Anhui Medical University between January 2016 and September 2023.

View Article and Find Full Text PDF

Background: The clinical characteristics and time-to-onset of thromboembolic events (TEEs) associated with combined oral contraceptives (COCs) remain unclear, our current study was committed to providing more data for risk evaluation and management of COCs treatment.

Research Design And Methods: This pharmacovigilance study was conducted in the FAERS database. We evaluated significant pharmacovigilance signals by using disproportionality analysis.

View Article and Find Full Text PDF

As a low-toxicity metal, aluminum has garnered increasing attention in relation to its impact on the human body; however, the specific mechanism of action remains unclear. To bridge this knowledge gap and facilitate practical applications, this study took 8-week-old ICR mice as the research object to study the effects of dietary addition of aluminum potassium sulfate on intestinal flora structure and liver. As the concentration of aluminum increased, it inhibited mice weight growth rate and significantly altered the composition of white blood cells in their bloodstream.

View Article and Find Full Text PDF
Article Synopsis
  • Ammonia loss is most significant during high-temperature aerobic composting (>50°C), causing nitrogen depletion and environmental pollution.
  • A bacterial strain named LL-8 was found to efficiently convert ammonia nitrogen, reducing volatile ammonia loss by 42.9% in chicken manure composting when applied at elevated temperatures.
  • Whole-genome analysis of LL-8 indicated its ability to assimilate ammonium nitrogen, making it a promising solution for improving nitrogen content in compost and mitigating ammonia-related air pollution.
View Article and Find Full Text PDF

Objective: To analyze patient satisfaction with letter-based communication of lung cancer screening (LCS) pulmonary nodule results.

Study Design: Prospective randomized controlled trial of LCS between May and December 2019.

Methods: All participants came from a prospective randomized controlled study on pulmonary nodule results in LCS with low-dose CT (LDCT) to analyze patient satisfaction, perception of information received via letters, preferred methods of receiving results, and dissatisfaction-related characteristics.

View Article and Find Full Text PDF

Persistent luminescent nanoparticles (PLNPs) are excellent luminescent materials, and near-infrared PLNPs are efficiently applied for biosensing and bioimaging due to their advantages of no excitation, excellent light stability and long afterglow. However, due to interference from the complex environment within organisms, single-mode imaging methods often face limitations in selectivity, sensitivity, and accuracy. Therefore, it is desirable to construct a dual-mode imaging probe strategy with higher specificity and sensitivity for bioimaging.

View Article and Find Full Text PDF

Photodynamic therapy (PDT) is a significant noninvasive therapeutic modality, but it is often limited in its application due to the restricted tissue penetration depth caused by the wavelength limitations of the light source. Two-photon (TP) fluorescence techniques are capable of having an excitation wavelength in the NIR region by absorbing two NIR photons simultaneously, which offers the potential to achieve higher spatial resolution for deep tissue imaging. Thus, the adoption of TP fluorescence techniques affords several discernible benefits for photodynamic therapy.

View Article and Find Full Text PDF
Article Synopsis
  • * DFT analysis revealed that CoN-Gra/TiNO showcased good catalytic activity with low overpotentials for both ORR and OER, while other catalysts like TiN-Gra/MNO showed poorer performance due to unfavorable orbital properties affecting adsorption energy.
  • * Machine learning techniques, particularly gradient boosting regression and symbolic regression, effectively predicted overpotentials for various catalysts and helped streamline the catalyst screening process to enhance experimental
View Article and Find Full Text PDF

The environmental impact from the waste disposal has been widely concerned around the world. The conversion of wastes to useful resources is important for the sustainable society. As a typical family of wastes, biomass materials basically composed of collagen, protein and lignin are considered as useful resources for recycle and reuse.

View Article and Find Full Text PDF
Article Synopsis
  • The importance of control valve positioners in chemical manufacturing is increasing as the industry evolves, particularly due to the impact of the flapper-nozzle system on system control.
  • Current research mainly focuses on modeling this system through computer simulations and dynamics, but traditional designs struggle with achieving linear control.
  • This paper introduces a new negative-pressure nozzle structure that addresses these limitations by using both simulations and experiments, leading to better air pressure supply and a wider range of linear pressure outputs, indicating its practical application potential.
View Article and Find Full Text PDF

An effective method was explored for the selective synthesis of sulfonamides and sulfenamides using sodium sulfinates and amines as starting materials. This method offers mild reaction conditions, a broad substrate scope, high efficiency, and readily accessible materials, making it suitable and an alternative strategy for the preparation of a variety of biologically or pharmaceutically active compounds.

View Article and Find Full Text PDF

This study aims to evaluate the efficacy and safety of Compound Qinlan Oral Liquid in the treatment of acute upper respiratory tract infection. Computer-based online searching of CNKI, VIP, SinoMed, Wanfang, ChiCTR, ClinicalTrials.gov, Cochrane Library, PubMed, EMbase, and Web of Science was performed to retrieve the randomized controlled trial(RCT) regarding Compound Qinlan Oral Liquid in the treatment of acute upper respiratory tract infection.

View Article and Find Full Text PDF

Background: A significant number of cross-sectional studies have explored the correlation between loneliness and problematic social media use. However, the causal relationship between these two key variables remains controversial, and the developmental relationship over time is unclear.

Methods: We conducted a one-year longitudinal study with 538 Chinese college students using questionnaires and employing cross-lagged and latent growth models to investigate the causal relationship and developmental dynamics between loneliness and problematic social media use.

View Article and Find Full Text PDF
Article Synopsis
  • The study focuses on developing a method to effectively monitor circRNA, which has potential as a biomarker for early diagnosis and treatment of diseases.
  • Researchers created a DNA octahedral amplifier (DOA) that uses a catalytic hairpin assembly (CHA) reaction to enhance the detection of circRNA in living cells through fluorescence resonance energy transfer (FRET).
  • By using the circHIPK3 associated with idiopathic pulmonary fibrosis as a target, the DOA demonstrated significant signal amplification, showcasing its potential for high-precision analysis and early diagnosis in medical applications.
View Article and Find Full Text PDF

A high-performance standalone planar field asymmetric waveform ion mobility spectrometry (p-FAIMS) system with a deconvolution algorithm (two-step particle swarm optimization algorithm, TSPSO) for overlapping peaks was developed to effectively detect chemical warfare agents (CWAs). Four CWA simulants were applied in this study to systemically evaluate the performance of the standalone p-FAIMS system. The experimental results showed that each CWA simulant in the mixture can be positively identified by carefully comparing the compensation voltage (CV) value of each peak in the FAIMS spectra for the mixture to the ones in the spectra acquired by using the same FAIMS system for the pure CWA simulant standards.

View Article and Find Full Text PDF

Personal exposure (PE) to polycyclic aromatic hydrocarbons (PAHs) and their derivatives in particulate matter with two aerodynamic sizes of 2.5 and 0.25 μm (PM and PM) from rural housewives was studied in the Fenwei Plain, China.

View Article and Find Full Text PDF

Bioimaging is widely used in various fields of modern medicine. Fluorescence imaging has the advantages of high sensitivity, high selectivity, noninvasiveness, in situ imaging, and so on. However, one-photon (OP) fluorescence imaging has problems, such as low tissue penetration depth and low spatiotemporal resolution.

View Article and Find Full Text PDF

Objective: Risk perception and disease cognition may influence the efficiency of lung cancer screening by affecting the participation rate. There is still some uncertainty regarding the association between risk perception and disease cognition and how they affect participation in lung cancer screening. Therefore, we explored the influence of risk perception and disease cognition on the willingness to participate in screening among people at high risk of lung cancer.

View Article and Find Full Text PDF
Article Synopsis
  • An out-of-plane vertical electric field of 1.0 V/Ang improves the stability of monolayer CdI by stabilizing its thermodynamic and kinetic properties.
  • * The electric field creates a Mexican-hat electronic state and causes significant changes in the conduction and valence bands, including strong spin polarization and energy level splitting.
  • * Overall, the electric field enhances the optical response of monolayer CdI, resulting in a broader range of effective absorption and a new peak in the optical spectrum that reduces excitonic effects.
View Article and Find Full Text PDF

Autophagy and the ubiquitin proteasome system are the two major processes for the clearance and recycling of proteins and organelles in eukaryotic cells. Evidence is accumulating that there is extensive crosstalk between the two pathways, but the underlying mechanisms are still unclear. We previously found that autophagy 9 (ATG9) and 16 (ATG16) proteins are crucial for full proteasomal activity in the unicellular amoeba .

View Article and Find Full Text PDF

There is a current lack of availability of therapeutics to treat Preeclampsia (PE), primarily due to the risk of harm to the fetus. Hypoxia‑inducible factor‑1α (HIF1α) is highly expressed in trophoblast cells and suppresses their invasive ability. Extensive studies have confirmed the positive effects of mesenchymal stem cell (MSC)‑derived exosomes on PE.

View Article and Find Full Text PDF
Article Synopsis
  • - Tire and road wear microplastics (TRWMPs) are significant pollutants linked to motor vehicles, causing environmental and health concerns, with a study conducted in Xi'an, China, during summer 2019 revealing a total concentration of 6522 ± 1455 ng/m of various harmful chemicals.
  • - Phthalates were found to be the most abundant component in TRWMPs, making up nearly two-thirds of the total, and concentrations varied throughout the day, peaking during evening rush hour, suggesting factors beyond vehicle numbers, such as weather and road conditions, influence TRWMP levels.
  • - While the non-carcinogenic risks from TRWMPs were within safe limits, the carcinogenic
View Article and Find Full Text PDF
Article Synopsis
  • * Results show significant reductions in indoor and personal PAH concentrations after switching to clean coal, with reductions of up to 93% for various PAH types, leading to improved pulmonary function.
  • * The findings suggest that using clean coal can substantially lower cancer risks associated with PAHs (by 60%-97%) and emphasizes the importance of transitioning to cleaner energy sources for better health outcomes.
View Article and Find Full Text PDF
Article Synopsis
  • Lung cancer is the top cause of cancer deaths globally, and this study evaluates low-dose CT screening's effectiveness in a Chinese population with both smokers and non-smokers, especially non-smoking women who often go unscreened.
  • In a trial involving 600 participants, including a significant number of women who were either non-smokers or passive smokers, the lung cancer incidence was found to be higher among non-smokers at 4.1% compared to 1.0% in smokers.
  • The research highlights the need for targeted screening programs for both active smokers and female non-smokers/passive smokers in Asia, while also calling for more studies to understand the long-term costs and benefits of such screening.
View Article and Find Full Text PDF