Publications by authors named "Feng Qin"

A novel catalyst was fabricated using a two-step nonthermal plasma method by regulating surface hydroxyl groups on Na/activated carbon (AC) with 0.1 wt% Pt loading (Pt/Na/AC (P&P)) and achieved high formaldehyde (HCHO) oxidation performance at ambient temperature. Based on characterization results, we found that in the first step of nonthermal plasma treatment under argon-water, the proportion of terminal OH groups (ter-OH groups) evidently increased.

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Ion channels are generally allosteric proteins, involving specialized stimulus sensor domains conformationally linked to the gate to drive channel opening. Temperature receptors are a group of ion channels from the transient receptor potential (TRP) family. They exhibit an unprecedentedly strong temperature dependence and are responsible for temperature sensing in mammals.

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Probing magnetic susceptibility of a microsized ferromagnet is a long-standing problem in condensed matter physics. Among various measuring methods for magnetic susceptibility including vibrating sample magnetometry and superconducting quantum interference device magnetometry, almost all require large-scale bulk samples or thick films. However, the quantitative measurement for magnetic susceptibility on a microscale nanoflake is a great challenge.

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Maize (Zea mays), which is a vital source of food, feed, and energy feedstock globally, has significant potential for higher yields. However, environmental stress conditions, including drought and salt stress, severely restrict maize plant growth and development, leading to great yield losses. Leucine-rich repeat receptor-like kinases (LRR-RLKs) function in biotic and abiotic stress responses in the model plant Arabidopsis (Arabidopsis thaliana), but their roles in abiotic stress responses in maize are not entirely understood.

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To identify the factors that influence the time to treatment (TT) in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). This study included a total of 324 patients with ISSNHL, who were treated at our department between September 2021 and May 2024. Basic information and audiological indicators of patients were collected, and their relationship with the TT was analyzed.

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Article Synopsis
  • Allergic diseases are on the rise, posing a significant health threat, particularly in Sichuan province, China, where a study analyzed allergen-specific immunoglobulin E (sIgE) levels in over 12,000 patients suspected of having allergies.
  • The study found that D1 and D2 allergens had the highest sensitization rates (22.97% and 23.33%, respectively), with men showing a higher rate of sensitization compared to women, and most patients with allergic rhinitis and asthma were sensitized to these allergens.
  • This research highlights the need for better identification and management of allergens, which can aid in preventing and treating allergic diseases.
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Purpose: To explore the relationship between hyperlipidemia and full-frequency idiopathic sudden sensorineural hearing loss (FFHL).

Patients And Methods: A total of 145 FFHL patients admitted from September 2021 to May 2024 were analyzed. Eighty-five patients with hyperlipidemia and 60 patients with normal serum lipids statistically analyze the patient's gender, age, onset time, accompanying symptoms, and serum lipids.

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  • Photodynamic therapy (PDT) is a cancer treatment that relies on the generation of singlet oxygen (O), with its effectiveness linked to the singlet oxygen quantum yield (Φ), which has measurement challenges due to poor signal-to-noise ratios and strict excitation wavelength requirements of existing methods.
  • The study introduces a novel approach to measure Φ using dimethyl sulfoxide (DMSO) as a solvent, which can be oxidized by singlet oxygen, allowing for a straightforward analysis through absorption spectrum changes without the need for additional chemical probes.
  • This new method simplifies the measurement of Φ and enhances accuracy, paving the way for broader applications in the evaluation of various photosensitizers, thereby advancing research in cancer treatment technologies
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Aims: To compare the efficacy of thyroid hormone receptor beta (THR-β) agonists, fibroblast growth factor 21 (FGF-21) analogues, glucagon-like peptide-1 receptor agonists (GLP-1RAs), GLP-1-based polyagonists, and pan-peroxisome proliferator-activated receptor (Pan-PPAR) agonists in the treatment of metabolic dysfunction-associated steatotic liver disease (MASLD).

Methods: A database search for relevant randomized double-blind controlled trials published until July 11, 2024, was conducted. Primary outcomes were the relative change in hepatic fat fraction (HFF) and liver stiffness assessed non-invasively by magnetic resonance imaging proton density fat fraction and elastography.

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Introduction: The trend of human migration to terrestrial high altitudes (HA) has been increasing over the years. However, no published prospective studies exist with follow-up periods exceeding 1 month to investigate the cardiac change. This prospective study aimed to investigate the changes in cardiac structure and function in healthy young male lowlanders following long-term migration to HA.

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Background: While deficiencies in vitamin B, folate, and vitamin B are linked to various human diseases, including anemia, depression, peripheral neuropathy, and cardiovascular disease (CVD), literature regarding the association between vitamin B, folate, and vitamin B and erectile dysfunction (ED) is scarce. We aimed to determine the dietary intake of vitamin B, folate, and vitamin B and ED in the United States population.

Methods: We extracted data from the 2001-2004 cycles of the National Health and Nutrition Examination Survey (NHANES).

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  • Catecholamines (CAs) are important biomarkers for diagnosing and treating diseases, but accurately separating them from biological samples is challenging due to their low levels and existing methods' limited selectivity.
  • Researchers developed a dual-recognition imprinted membrane (BA-MIM) that combines boron affinity and molecular imprinting for highly selective capture and release of CAs, showing excellent adsorption capacity and reusability.
  • An innovative analytical method using BA-MIM and ultrahigh-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) was created, enabling sensitive detection of CAs in rat brain tissue and linking CA metabolism to kidney disease in a specific rat model.
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Introduction: The dysbiosis of the oral microbiome is associated with the progression of various systemic diseases, including diabetes. However, the precise causal relationships remain elusive. This study aims to investigate the potential causal associations between oral microbiome and type 2 diabetes (T2D) using Mendelian randomization (MR) analyses.

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Small-molecule prodrug nanoassembly technology with a unique advantage in off-target toxicity reduction has been widely used for antitumor drug delivery. However, prodrug activation remains a rate-limiting step for exerting therapeutic actions, which requires to quickly reach the minimum valid concentrations of free drugs. Fortunately, we find that a natural compound (BL-193) selectively improves the chemotherapy sensitivity of breast cancer cells to podophyllotoxin (PPT) at ineffective dose concentrations.

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Multiple sclerosis (MS) is a debilitating demyelinating disease characterized by remyelination failure attributed to inadequate oligodendrocyte precursor cells (OPCs) differentiation and aberrant astrogliosis. A comprehensive cell atlas reanalysis of clinical specimens brings to light heightened clusterin (CLU) expression in a specific astrocyte subtype links to active lesions in MS patients. Our investigation reveals elevated astrocytic CLU levels in both active lesions of patient tissues and female murine MS models.

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Gegen Qinlian Decoction (GGQLT) is a traditional Chinese herbal medicine that has been reported to have a significant therapeutic effect in the management of type II diabetes mellitus (T2DM). In this study, we constructed a T2DM rat model by feeding a high-fat diet and injecting streptozotocin (STZ) and tested the effects of feeding GGQLT and fecal transplantation on the physiological indices, microbiota, and metabolism of rats. The results showed that the administration of GGQLT can significantly improve the growth performance of rats and has a remarkable antihyperlipidemic effect.

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  • Plant pathogens release effectors that can weaken the host's immune defenses, leading to a situation known as effector-triggered susceptibility (ETS).
  • In response, plants utilize special receptors called nucleotide-binding leucine-rich repeat receptors (NLRs) to identify these effectors and activate their immune response, known as effector-triggered immunity (ETI).
  • Recent studies by Liu et al. and Zhang et al. have shown significant advances in managing rice blast disease by manipulating the processes of ETS and ETI.
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Understanding the dietary preferences and ecological niche characteristics of mammals not only reveals their adaptive strategies under environmental changes but also reveals the interspecific relationships and coexistence mechanisms among sympatric species. Nevertheless, such data are scarce for rodents inhabiting areas spanning a wide altitude range. This study employed DNA metabarcoding technology to analyze the stomach contents of , , and , aiming to investigate their dietary compositions and diversity in the Meili Snow Mountain in Yunnan Province, China.

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Asperphenol A (), a new isoprenyl-phenol-type meroterpenoid, was isolated from the mangrove endophytic fungus sp. GXNU-Y65 together with five known compounds (-. All structures were assigned using extensive NMR spectroscopic data and electronic circular dichroism (ECD) calculations.

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Background: Non-alcoholic steatohepatitis (NASH), an escalating global health concern, is a primary factor behind cirrhosis, liver transplantation, and hepatocellular carcinoma. Effective treatments remain elusive. Danggui-Shaoyao-San (DGSY), a classic famous prescription employed in treating NASH, could hold promise, although its molecular underpinnings are still under investigation.

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Antiandrogen is part of the standard-of-care treatment option for metastatic prostate cancer. However, prostate cancers frequently relapse, and the underlying resistance mechanism remains incompletely understood. This study seeks to investigate whether long non-coding RNAs (lncRNAs) contribute to the resistance against the latest antiandrogen drug, darolutamide.

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