Based on a typical ozone (O) pollution process in Jinan City from June 16 to 26, 2021, the variation characteristics of O and its precursor volatile organic compounds (VOCs) during different pollution periods (clean period (CP), pollution rise period (PRP), heavy pollution period (HPP), and pollution decline period (PDP)) in the urban area were analyzed. Both positive matrix factorization (PMF) and an observation-based model (OBM) were used to identify the main sources of VOCs, O production mechanisms, and sensitive species. The results showed that the average value of (O-8h) during the HPP period in the urban area was (246.
View Article and Find Full Text PDFPurpose: The purpose of this study was to report the distribution of mean ocular perfusion pressure (MOPP) and its associated factors in Chinese children.
Methods: We enrolled 3048 grade 1 students and 2258 grade 7 students of the Anyang Childhood Eye Study in central China. Systolic and diastolic blood pressure (SBP and DBP) were recorded with a digital automatic sphygmomanometer.
Aim: To compare the Barrett True-K formula with other formulas integrated in Lenstar 900 to predict intraocular lens (IOL) power after small-incision lenticule extraction (SMILE).
Methods: A theoretical prospective study was performed to predict the ratio of equivalent IOL power before and after SMILE using the SRK/T (Sanders, Retzlaff, Kraff/theoretical), Holladay 1, Haigis, and Barrett True-K formulas and compare the stability of their predictions. The study included 54 eyes (54 cases) with a manifest refraction spherical equivalent (MRSE) of -4.
Purpose: To evaluate the ocular biological parameter difference between scleral corneal cross-linking (CXL) and control eyes in rhesus monkeys by using a rebound tonometer, A-scan ultrasonography, retinoscopy, optical coherence tomography, and electroretinography (ERG).
Methods: Six rhesus monkeys were used in this study, with ages ranging from 3 to 3.5 years.
To evaluate the differences between the estimated and measured lenticule thickness and relationships in myopic eyes with different refractive errors after small-incision lenticule extraction (SMILE). This prospective study included a total of 190 eyes (96 patients) with a manifest refraction spherical equivalent (MRSE) of -6.16 ± 1.
View Article and Find Full Text PDFBackground And Aims: Nowadays, the plant family 1 glycosyltransferases (UGTs) are attracting more and more attention since members of this family can improve the properties of secondary metabolites and have significantly enriched the chemical species in plants. Over the past decade, most studies on UGTs have been conducted in Arabidopsis thaliana and they were proved to play diverse roles during the plant life cycle. The Zea mays (maize) GT1 family comprises a large number of UDP-glycosyltransferase (UGT) members.
View Article and Find Full Text PDFAim: To evaluate and compare the uniformity of angle Kappa adjustment between Oculyzer and Topolyzer Vario topography guided ablation of laser keratomileusis (LASIK) by EX500 excimer laser for myopia.
Methods: Totally 145 cases (290 consecutive eyes )with myopia received LASIK with a target of emmetropia. The ablation for 86 cases (172 eyes) was guided manually based on Oculyzer topography (study group), while the ablation for 59 cases (118 eyes) was guided automatically by Topolyzer Vario topography (control group).
Graefes Arch Clin Exp Ophthalmol
January 2017
Purpose: To investigate the effects of no correction versus full correction on myopia progression in Chinese children over a period of 2 years.
Methods: Myopia was defined as cycloplegic spherical equivalent (SE) of ≤ -0.50 D.
The plant family 1 UDP-glycosyltransferases (UGTs) are the biggest GT family in plants, which are responsible for transferring sugar moieties onto a variety of small molecules, and control many metabolic processes; however, their physiological significance in planta is largely unknown. Here, we revealed that two Arabidopsis glycosyltransferase genes, UGT79B2 and UGT79B3, could be strongly induced by various abiotic stresses, including cold, salt and drought stresses. Overexpression of UGT79B2/B3 significantly enhanced plant tolerance to low temperatures as well as drought and salt stresses, whereas the ugt79b2/b3 double mutants generated by RNAi (RNA interference) and CRISPR-Cas9 strategies were more susceptible to adverse conditions.
View Article and Find Full Text PDFPurpose: To report the design, methods and baseline data of the Anyang Childhood Eye Study (ACES), aiming to determine the prevalence, incidence and risk factors of myopia and other ocular diseases in children in central China.
Methods: The ACES was a school-based cohort study conducted in Anyang city. Students have been examined and will be followed-up annually for 3-5 years.
Zhonghua Yan Ke Za Zhi
April 2013
Gene engineering technology provides new methods for medical research. The application of transgenic animals and knock out animals makes it possible to study the biological characteristics of genes associated with some human diseases in vivo. Transgenic mice were first achieved in the early 1980s, while they were used extensively in the field of ophthalmology doing some research a few years later after that.
View Article and Find Full Text PDFObjective: To investigate the clinical efficacy and safety of 0.1% bromfenac sodium hydrate ophthalmic solution in myopia and astigmatism eyes after sub-Bowman keratomileusis (SBK) METHODS: A case control study. Number of patients with low to moderate myopia (-6.
View Article and Find Full Text PDFZhonghua Yan Ke Za Zhi
February 2013
UVA-riboflavin cross-linking is an effective approach to increase the mechanical and biochemical rigidity of the collagen fiber, which has been used in treating some corneal diseases such as keratoconus, and might become a new treatment modality for strengthening scleral tissue to prevent progressive myopia, so the safety of the new therapy has be paid attention widely. This article focus on the diffusion process and saturation judgment of riboflavin and describes the effect of riboflavin, direct UV damage, photochemical damage and the prevention of side effects in cross-linking therapy.
View Article and Find Full Text PDFZhonghua Yan Ke Za Zhi
May 2012
It is very important to avoid inadequate patients to perform excimer laser keratectomy in order to prevent from surgical complications. The ametropic eyes with corneal guttata is considered very carefully whether to perform excimer laser corneal ablation or not, especially for the patient with corneal guttata companied by Fuchs endothelial dystrophy family history is contraindicated to perform laser corneal refractive surgery.
View Article and Find Full Text PDFZhonghua Yi Xue Za Zhi
March 2012
Objective: To identify differentially expressed lumican in scleral tissue of eyes with primary open-angle glaucoma (POAG) and high myopia (HM).
Methods: Total RNA was isolated from scleral tissue of cadaveric eyes derived from normal donors, patient's eyes with diagnosed glaucoma and high myopia who accepted trabeculectomy. RNA was amplified, RT-PCR was used to measure the levels of mRNA.
Zhonghua Yan Ke Za Zhi
July 2011
With the development of excimer laser technologies, the corneal refractive surgical procedures are improved constantly and the indication of excimer laser keratectomy is expanded. In clinic, PRK or LASEK or PTK or LASIK were performed on the eyes of granular corneal dystrophy with refractive error and the early results were satisfied, but the reoccurrence and server opacity of cornea are worried. Is this corneal disease the indication of excimer laser keratectomy? Nowadays, the exact indication for the disease should be declared in clinic.
View Article and Find Full Text PDFPurpose: To compare refractive performance of implantation of an iris-fixated phakic intraocular lens (PIOL) through a novel trapezoidal corneal and a scleral tunnel incision.
Methods: Sixty-nine eyes selected to undergo PIOL implantation were randomly assigned to 1 of 2 groups: 5.2-mm trapezoidal corneal incision (TCI), 34 eyes; 5.
Purpose: High myopia is a severe hereditary ocular disease leading to blindness. LAMA1 (alpha subunit of laminin) is a promising candidate gene for high myopia present in the MYP2 (myopia 2) region. The purpose of this study was to determine if high myopia is associated with single nucleotide polymorphism (SNP) variants in LAMA1 in Chinese subjects.
View Article and Find Full Text PDFZhonghua Yan Ke Za Zhi
November 2010
Collagen can link between or within collagen molecules through the covalent bond, which leads to increasing the tension and stability of collagen fiber. Collagen cross-linking had been widely used in other industries, the recent research showed that cross-linking of scleral collagen increased the scleral biomechanical rigidity efficiently, which might become a new treatment modality for strengthening scleral tissue to prevent progressive myopia. This review describes the sclera collagen characteristics of progressive myopia, traditional treatment and sclera collagen cross-linking therapy.
View Article and Find Full Text PDFZhonghua Yan Ke Za Zhi
November 2010
Objective: To study the accuracy of different formulas predicting intraocular lens (IOL) power after excimer laser keratorefractive surgery in order to calculate the diopter of IOL accurately in the clinical practice.
Methods: One hundred and eleven cases (222 eyes) were collected in this study and were divided into two groups (A and B) according to their axial length. Fifty-nine cases (118 eyes) with axial lengths of 24-26 mm were taken as group A, and 52 cases (104 eyes) with axial length of more than 26 mm were taken as group B.
Aim: To study the dynamic character of aberration between the cornea and the ocular with aging, and to evaluate the symmetry of the aberrations between right and left eye in order to supply the data for clinic to do the refractive surgery reasonably.
Methods: This is a comparative case series study. 82 normal cases (164 eyes) including 37 females (74 eyes) and 45 males (90 eyes) were recruited through the routine examinations, Topolyzer and wavefront analysis.
Zhonghua Yi Xue Za Zhi
February 2010
Zhonghua Yan Ke Za Zhi
July 2009
Objective: To investigate morphologically the different changes of cornea tissue between thick and thin cornea flap with confocal microscope, and to compare visual function between thick and thin cornea flap after LASIK.
Methods: 70 cases (70 eyes) who had received LASIK were divided into the thin cornea flap group (36 eyes, group A) and the thick cornea flap group (34 eyes, group B). The age was (23 +/- 5) years old, spherical equivalent diopter (SE) were ( - 4.
Objective: To investigate the efficacy and safety of wavefront guided (WG) LASIK for the myopia and astigmatism.
Methods: This study is a randomized control trial. 42 cases (78 eyes) were collected in the study through the routine examinations and wavefront analysis, which were divided into two groups (A and B).