Publications by authors named "Fen-yu Li"
Article Synopsis
- The text mentions a correction related to a previous article published with the DOI: 10.3389/fmicb.2019.02838.!
- It indicates that there may have been errors or updates that needed to be addressed in the original article.!
- The correction aims to clarify information and ensure the accuracy of the published research within the field of microbiology.!
Article Synopsis
- CRISPR-Cas13a, an RNA-targeting system, exhibits unique cleavage activities for single-stranded RNA and was studied through whole genome sequences of 11 strains compared to 18 others to analyze its diversity and occurrence.
- The research found a wide distribution of various CRISPR-Cas types among the genomes, with notable absence in 20.5% of strains, and highlighted the highly divergent nature of Cas13a effectors, yet their ability to impede bacterial growth remained consistent.
- Analysis of CRISPR spacers revealed significant diversity, with only 4.4% shared between strains, while the organization and prevalence of different CRISPR-Cas types underscored the evolutionary relationships and characteristics of these
Correlations between drug resistance of Beijing/W lineage clinical isolates of Mycobacterium tuberculosis and sublineages: a 2009-2013 prospective study in Xinjiang province, China.
Xian-hua Wang Ai-guo Ma Xiu-xia Han Xiao-ming Gu Li-ping Fu Peng-gang Li Fen-yu Li Hui Liang Li-jie Wang
Med Sci Monit
May 2015
Background: The prevalence of drug-resistant tuberculosis (TB) in Xinjiang is higher than in other regions of China, and Beijing/W lineage Mycobacterium tuberculosis (MTB) is the dominant strain of MTB in Xinjiang. However, information on multidrug-resistant (MDR) and extensively drug-resistant (XDR) TB, particularly the correlation between MDR and the Beijing/W lineage and the correlation between drug resistance and the Beijing/W sublineage strains, is limited.
Material/methods: We conducted a prospective study to describe the prevalence of MDR/XDR TB, Beijing/W lineage and sublineage strains in Xinjiang in China from 2009 to 2013.