Publications by authors named "Fen-Fang Miao"
Biotechnol Bioeng
July 2024
Article Synopsis
- Pathogenic bacterial membrane proteins (MPs) are important targets for vaccines and antibiotics, though their hydrophobic nature complicates proper folding in cells.
- A new method has been developed to enhance the solubility of MP antigens by creating multi-epitope chimeric antigens (ChA) and using protein folding helpers.
- The engineered strain produced a high yield of highly soluble ChA, which is significant for its potential application in vaccine development and industrial processes.
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