Pharmacokinetic studies of soyalkaloid A from Portulaca oleracea L. using ultra high-performance liquid chromatography electrospray ionization quadrupole-time of flight mass spectrometry and its antioxidant activity.

Soyalkaloid A was isolated from Portulaca oleracea L. for the first time in our laboratory and then a rapid and sensitive ultra-high-performance liquid chromatography electrospray ionization quadrupole-time of flight mass spectrometry (UHPLC-ESI-Q-TOF/MS) method with hesperidin as internal standard (IS) was developed and validated to investigate the pharmacokinetics of soyalkaloid A in rats after oral and intravenous administrations. The analysis was achieved on an Agilent Zorbax Eclipse Plus C Column (2.

A new alkaloid from L. and its antiacetylcholinesterase activity.

A new alkaloid, (10, 12)-9-ureidooctadeca-10, 12-dienoic acid, named oleraurea and 10 known compounds, -hydroxybenzaldehyde , -hydroxybenzoic acid , -hydroxyacetophenone , benzamide , (--coumaramide , ()-ferulamide , soyalkaloid A , -carboline-3-carboxylic acid , 2, 3, 4, 9-tetrahydro--pyrido [3, 4-] indole-3-carboxylic acid , (1, 3)-1-methyl-1, 2, 3, 4-tetrahydro--carboline-3-carboxylic acid were obtained from L., in which, compounds , , were isolated from the plant for the first time. The structure of the compound was identified using spectroscopic methods including 1D and 2D NMR, HR-ESI-TOF-MS.

An isoindole alkaloid from Portulaca oleracea L.

A novel isoindole alkaloid named oleraisoindole (1), together with six known compounds, 7'-ethoxy-trans-feruloyltyramine (2), N-trans-feruloyltyramine (3), N-trans-feruloyl-3-methoxytyramine (4), N-trans-p-coumaroyltyramine (5) aurantiamide (6) and ferulic acid methyl ester (7) were isolated from Portulaca oleracea L. Compounds 2 and 7 were isolated for the first time from this plant. Compound 1 was identified using spectroscopic methods including HR-ESI-TOF-MS, 1D-NMR, 2D-NMR.