Publications by authors named "Femke B Lamers-Karnebeek"
Objective: Ultrasonography (US) can be used for treatment decisions in RA patients. This study investigated the added value of US to clinical variables in predicting flare in RA patients with longstanding low disease activity when stopping TNF inhibitors (TNFi).
Methods: Cox models with and without using US added to clinical variables were developed in the Potential Optimization of Expediency of TNFi-UltraSonography study.
Objective: The prevalence of periodontitis is increased in patients with rheumatoid arthritis (RA), and the severity of periodontitis can affect the level of arthritis. Porphyromonas gingivalis is one of the main bacteria involved in periodontitis. Our aim was to determine if there are differences in the innate immune response against P gingivalis between healthy controls and RA patients.
View Article and Find Full Text PDFObjective: To evaluate the risk of having a disease flare in patients with rheumatoid arthritis (RA) with low disease activity (LDA) or in remission when deescalating (tapering or stopping) disease-modifying antirheumatic drug (DMARD) therapy.
Methods: A search in medical databases including publications from January 1950 to February 2015 was performed. Included were trials and observational studies in adults with RA who were in LDA or remission, evaluating ≥ 20 patients tapering or stopping DMARD.
Article Synopsis
- The study aimed to evaluate the reliability of ultrasonography (US) in identifying inflammatory and structural issues in patients with knee osteoarthritis (OA).
- Thirteen early knee OA patients were examined by 11 experienced sonographers, who used specific scoring methods to assess synovitis and other knee joint abnormalities.
- The results showed that the reliability of US scoring for synovitis and cartilage damage was moderate to good, suggesting that with a standardized protocol, US can effectively identify pathological changes in knee OA.