Publications by authors named "Felix Thalen"
Rapid advances in high-throughput DNA sequencing technologies have enabled large-scale whole genome sequencing (WGS) studies. Before performing association analysis between phenotypes and genotypes, preprocessing and quality control (QC) of the raw sequence data need to be performed. Because many biostatisticians have not been working with WGS data so far, we first sketch Illumina's short-read sequencing technology.
View Article and Find Full Text PDFLow-coverage whole-genome sequencing (also known as "genome skimming") is becoming an increasingly affordable approach to large-scale phylogenetic analyses. While already routinely used to recover organellar genomes, genome skimming is rather rarely utilized for recovering single-copy nuclear markers. One reason might be that only few tools exist to work with this data type within a phylogenomic context, especially to deal with fragmented genome assemblies.
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- Different animals can heal and grow back parts in different ways, even planarian flatworms that are famous for this.
- Researchers studied 40 species of these flatworms to understand how they regenerate their heads, discovering that some can heal really well while others can't at all.
- They found that a special process called Wnt signalling is important for regeneration but also plays a role in reproduction, suggesting there might be a balance between having babies and healing.