Publications by authors named "Felix Sah"
Article Synopsis
- - This study focuses on identifying the cellular origins of common childhood brain tumors (ependymoma, pilocytic astrocytoma, and medulloblastoma) using a human cerebellar atlas, which offers a more accurate reference than previous methods that compared human tumors to mouse tissues.
- - Using a large dataset of normal and tumor-specific gene expressions, the researchers suggest that different brain tumors can arise from various progenitor cells in the cerebellum and have distinct lineage origins.
- - The findings indicate that tumors may consist of cells resembling different types from a specific developmental lineage, highlighting the complexity of tumor origins and suggesting potential therapeutic strategies based on identified tumor-specific genes.
