Publications by authors named "Felix Lau"
Objective: The study investigates the prognostic impact of dyskalemias in patients hospitalized with heart failure with mildly reduced ejection fraction (HFmrEF).
Background: Although dyskalemias represent a common complication in patients with heart failure (HF) and reduced left ventricular ejection fraction (LVEF), data concerning the prevalence and prognostic impact of dyskalemias in HFmrEF is limited.
Methods: Consecutive patients with HFmrEF were retrospectively included at one institution from 2016 to 2022.
This study investigates age-related differences and outcomes in patients hospitalized with heart failure with a mildly reduced ejection fraction (HFmrEF). The characterization of patients with HFmrEF and the prognostic value of age has rarely been investigated. Patients with HFmrEF were retrospectively included at one institution between 2016 and 2022.
View Article and Find Full Text PDFObjective: This study investigates the prevalence and prognostic impact of diastolic dysfunction (DD) in patients hospitalized with heart failure (HF) with mildly reduced ejection fraction (HFmrEF) in sinus rhythm.
Background: Data regarding the prognostic impact of DD in patients with HFmrEF is limited.
Methods: From 2016 to 2022, all patients hospitalized with HFmrEF (i.
Objective: The study investigates the characteristics and prognostic impact of different heart failure (HF) etiologies in patients with heart failure with mildly reduced ejection fraction (HFmrEF).
Background: Data regarding the characterization of patients with HFmrEF and their outcomes is scarce.
Methods: Consecutive patients with HFmrEF (i.
Aims: Data regarding the characterization and outcomes of patients with heart failure (HF) with mildly reduced ejection fraction (HFmrEF) is scarce. This study investigates the characteristics and prognostic impact of native aortic valve diseases (AVD) in patients with HFmrEF.
Methods And Results: Consecutive patients hospitalized with HFmrEF (i.
Aims: The study investigates the prognosis of atrial fibrillation (AF) in patients with heart failure with mildly reduced ejection fraction (HFmrEF). Data concerning the prognostic impact of AF in patients with HFmrEF is scarce.
Methods And Results: Consecutive patients with HFmrEF [i.
Objective: The study investigates the prognostic impact of the severity and etiology of chronic kidney disease (CKD) in patients with heart failure with mildly reduced ejection fraction (HFmrEF).
Background: Data regarding the outcomes in patients with CKD in HFmrEF is scarce.
Methods: Consecutive patients with HFmrEF were retrospectively included at one institution from 2016 to 2022.
Article Synopsis
- The study examines how previous left ventricular ejection fraction (LVEF) affects prognosis in patients with mildly reduced ejection fraction (HFmrEF) heart failure, a condition often overlooked in terms of prognostic impact.
- It retrospectively analyzed 689 patients from 2016 to 2022, categorizing them into three groups based on changes in LVEF: stable, improved, and deteriorated.
- Results showed no significant differences in all-cause mortality or hospital readmissions among the groups at 12 and 30 months, indicating that changes in LVEF do not significantly influence patient outcomes in this population.
Objective: The present study aims to clarify the prevalence and prognostic impact of anaemia and iron deficiency in patients with heart failure with mildly reduced ejection fraction (HFmrEF).
Background: The prognostic impact of anaemia and iron deficiency in HFmrEF has not yet been clarified.
Methods: Consecutive patients with HFmrEF were retrospectively included at one institution from 2016 to 2022.
Article Synopsis
- Mitral valve regurgitation (MR) is prevalent among patients with mildly reduced ejection fraction heart failure (HFmrEF), yet data on its impact is limited.
- A study of over 2,000 hospitalized HFmrEF patients found that those with MR had significantly higher risk of all-cause mortality and hospital readmissions for worsening heart failure compared to those without MR.
- The findings also indicated that the severity of MR correlates with increased mortality risk, and secondary MR is associated with better outcomes than primary MR.
Aims: The study sought to comprehensively investigate the effect of heart failure (HF) pharmacotherapies in patients with HF with mildly reduced ejection fraction (HFmrEF). In the absence of randomized controlled trials, guideline recommendations concerning HF-related therapies in patients with HFmrEF are limited.
Methods And Results: Consecutive patients hospitalized with HFmrEF were retrospectively included at one institution from 2016 to 2022.
Article Synopsis
- The study looked at how body mass index (BMI) affects patients with heart failure who have mildly reduced heart function.
- It found that patients with lower BMI had a higher chance of dying within 30 months compared to those with higher BMI.
- This suggests that being overweight might actually help some patients with this type of heart failure live longer, which is called the "obesity paradox."
Background: Data regarding the characterization and outcomes of diabetics with heart failure with a mildly reduced ejection fraction (HFmrEF) is scarce. This study investigates the prevalence and prognostic impact of type 2 diabetes in patients with HFmrEF.
Methods: Consecutive patients with HFmrEF (i.
Article Synopsis
- * It included 2,184 patients, revealing that those with COPD had a higher risk of all-cause mortality (45% vs. 30%) and re-hospitalization due to worsening heart failure compared to those without COPD.
- * The findings suggest that COPD significantly worsens outcomes for patients hospitalized with HFmrEF, indicating a need for targeted management strategies for this population.
Article Synopsis
- Cardiac remodeling happens in people with heart failure (HF) and helps doctors see how serious the disease is.
- A study looked at 1881 patients with a specific type of heart failure (called HFmrEF) from 2016 to 2022 to see how septal hypertrophy (a condition where part of the heart muscle gets thicker) affected them.
- Although having septal hypertrophy wasn't linked to higher death rates, it was connected to a higher chance of being hospitalized again due to heart problems in the following months.
Article Synopsis
- This study examines the effectiveness of NT-proBNP as a biomarker for diagnosing and predicting outcomes in patients with heart failure and mildly reduced ejection fraction (HFmrEF), focusing on their kidney function (eGFR).
- Among the 755 patients analyzed, those with acute decompensated heart failure (ADHF) showed significantly higher NT-proBNP levels compared to those without, indicating its potential as a diagnostic tool.
- Higher NT-proBNP levels (> 3946 pg/mL) were linked to increased rates of death over 30 months, but its predictive value was diminished in patients with severely reduced kidney function (eGFR < 30 mL/min).
Prognostic impact of acute decompensated heart failure in patients with heart failure with mildly reduced ejection fraction.
Eur Heart J Acute Cardiovasc Care
February 2024
Article Synopsis
- This study looked at how acute decompensated heart failure (ADHF) affects patients who have heart failure with mildly reduced ejection fraction (HFmrEF).
- Researchers found that patients with ADHF had a much higher chance of dying or being hospitalized again compared to those without ADHF.
- The conclusion is that having ADHF is common and makes health outcomes worse for patients with HFmrEF.
Objectives: The primary objective is to evaluate the incidence of occult nodal metastasis in patients undergoing total laryngectomy with cN0 disease. Other objectives are to compare the survival between different treatments of the neck, identify possible associated risk factors, and evaluate the effectiveness of elective neck dissection in this population with regards to oncological outcomes.
Study Design: Retrospective review.