Publications by authors named "Felix Corre"
Aim: Endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) are the two main techniques used for endoscopic resection of superficial rectal tumours. The aim of this study was to compare the outcomes of ESD and EMR in treating superficial rectal tumours.
Method: A retrospective observational study was conducted at two French centres including all patients treated with ESD or EMR for superficial rectal tumours.
Background And Aims: We aimed to evaluate the feasibility, safety and efficacy of endoscopic submucosal dissection for recurrent rectal neoplastic lesions after transanal microsurgery of superficial rectal neoplasms.
Methods: Multicenter retrospective study.
Main Outcomes: recurrence at first endoscopic follow-up, En bloc, R0 and curative resections.
Article Synopsis
- This study aimed to evaluate the effectiveness and safety of two procedures—peroral endoscopic myotomy with septotomy (POEM+S) and without septotomy (POEM-S)—in treating symptomatic epiphrenic diverticula (ED) alongside motility disorders.
- Conducted across 21 international centers from 2014 to 2023, the study included 85 patients, measuring clinical success primarily through the Eckardt score.
- Results indicated that both procedures had similar clinical success rates (83% for POEM+S vs. 86.8% for POEM-S), technical success, and adverse event rates, but POEM-S patients had a longer hospital stay.
Article Synopsis
- The study aimed to compare long-term outcomes for patients with high-risk T1 colorectal cancer who underwent endoscopic resection, assessing the effectiveness of additional surgery versus surveillance alone.
- Data was collected from patients treated at 14 centers between 2012 and 2019, with the primary outcome focusing on cancer recurrence or death within 48 months.
- Results showed no significant difference in the rates of death or cancer recurrence between the two groups, suggesting that additional surgery may not provide benefits for these patients.
Background And Aims: Endoscopic submucosal dissection (ESD) is challenging for appendicular lesions. We report the outcomes of ESD in this context.
Methods: We collected data of ESD procedures for appendiceal neoplasia in a multicenter prospective registry.
Sarcopenia, defined as decreased muscle mass and strength, can be evaluated by a computed tomography (CT) examination and might be associated with reduced survival in patients with carcinoma. The prognosis of patients with metastatic pancreatic carcinoma is poor. The FOLFIRINOX (a combination of 5-fluorouracil, irinotecan, and oxaliplatin) chemotherapy regimen is a validated first-line treatment option.
View Article and Find Full Text PDFAirborne transmission of SARS-Cov2: What consequences for digestive endoscopy?
United European Gastroenterol J
March 2023
The SARS-Cov-2 disease disrupted essential hospital procedures, such as gastrointestinal (GI) endoscopy, due to concerns about air transmission and the risk of exposing health care workers. With the spread of the pandemic, air transmission was considered as the main source of SARS-Cov2 transmission. This raised the problem of transmission by aerosolization of viral particles in operating rooms as well as endoscopy units.
View Article and Find Full Text PDFEvidence for the modes of transmission of SARS-CoV-2 remains controversial. Recently, the potential for airborne spread of SARS-CoV-2 has been stressed. Air circulation in gastrointestinal light source boxes and endoscopes could be implicated in airborne transmission of microorganisms.
View Article and Find Full Text PDFPredictive factors of radiofrequency ablation failure in the treatment of dysplastic Barrett's esophagus.
Clin Res Hepatol Gastroenterol
January 2023
Introduction: Radiofrequency ablation (RFA) has become the recommended endoscopic treatment for flat dysplastic Barrett's esophagus. However, the outcomes of this treatment are variable across European countries. Our aim was to report the results of a French high-volume center, and to investigate factors associated with treatment failure.
View Article and Find Full Text PDFIntroduction: Proton pump inhibitors (PPIs) are one of the most prescribed classes of drugs worldwide as a first-line treatment of acid-related disorders. Although adverse effects are rare and rapidly reversible after a short exposure, concerns have been recently raised about a greater toxicity on cardiovascular health after a longer exposure, especially when combined with clopidogrel. We aimed to evaluate the safety of long-term PPI use on cardiovascular health in patients with known atheromatous cardiovascular disease.
View Article and Find Full Text PDFArticle Synopsis
- - The study aims to evaluate long-term symptoms and quality of life in COVID-19 patients over 100 days post-hospitalization.
- - A total of 120 patients were surveyed, revealing common ongoing issues like fatigue (55%), dyspnea (42%), and memory loss (34%), with no significant differences between those treated in regular wards versus ICUs.
- - The quality of life for both groups showed notable impairments, particularly in mobility and mental health, suggesting that many COVID-19 survivors experience lingering effects that warrant further research with larger sample sizes.
Article Synopsis
- The study aimed to identify predictive factors for unfavorable outcomes in COVID-19 patients hospitalized in Paris, focusing on factors leading to the need for artificial ventilation or death.
- Researchers analyzed data from 279 COVID-19 patients, finding 31.5% experienced unfavorable outcomes, with key risk factors including age, weight, respiratory rate, fever, and specific blood markers.
- A nomogram was developed to predict the probability of adverse outcomes within 14 days, providing a useful tool for early detection and improving clinical care for at-risk patients.
Article Synopsis
- - The CURB-65 score is used to predict mortality in community-acquired pneumonia, but its relevance for COVID-19 patients' outpatient treatment decisions is uncertain.
- - A study analyzed 279 hospitalized COVID-19 patients, revealing that CURB-65 scores indicated varying levels of risk for poor outcomes, with 31.5% experiencing severe complications like mechanical ventilation or death.
- - Findings suggest that CURB-65 is not a reliable tool for determining which COVID-19 patients can be treated at home, as even those categorized as low risk still faced significant dangers.