Comprehensive health risk assessment of urban ambient air pollution (PM, NO and O) in Ghana.

Urbanization and industrialization have drastically increased ambient air pollution in urban areas globally from vehicle emissions, solid fuel combustion and industrial activities leading to some of the worst air quality conditions. Air pollution in Ghana causes approximately 28,000 premature deaths and disabilities annually, ranking as a leading cause of mortality and disability-adjusted life years. This study evaluated the annual concentrations of PM NO and O in the ambient air of 57 cities in Ghana for two decades using historical and forecasted data from satellite measurements.

Response surface methodology as a tool to optimize the extraction of bioactive compounds from plant sources.

Response surface methodology (RSM) is a widely used mathematical and statistical technique for modeling and optimizing the process for the extraction of bioactive compounds. This review explains the optimization approach through the use of experimental design and empirical models for response prediction and the utilization of the desirability function for multiple response optimization. This paper also reviews recent studies on the application of RSM to optimize bioactive compound extraction processes such as conventional solvent extraction, microwave-assisted extraction, supercritical fluid extraction, and ultrasound-assisted extraction.

Simultaneous Optimization of Microwave-Assisted Extraction of Phenolic Compounds and Antioxidant Activity of Avocado ( Mill.) Seeds Using Response Surface Methodology.

This study was designed to optimize three microwave-assisted extraction (MAE) parameters (ethanol concentration, microwave power, and extraction time) of total phenolics, total flavonoids, and antioxidant activity of avocado seeds using response surface methodology (RSM). The predicted quadratic models were highly significant ( < 0.001) for the responses studied.