Publications by authors named "Felipe Vitorio"

Article Synopsis
  • - The study focused on creating and analyzing new coumarin-imidazopyridine hybrid ligands and their zinc(II) complexes, achieving a successful synthesis with yields between 56-90%.
  • - The synthesized complexes showed significant antiviral effects against the Zika virus, with some demonstrating better activity than the standard antiviral ribavirin.
  • - Investigations into how these compounds work revealed they can disrupt both viral entry and replication, providing insights into their mechanisms and potential for further development.
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Coumarins are natural products characterized as 1,2 benzopyrones widely distributed in plants, as well as, in many species of fungi and bacteria. Nowadays, many synthetic procedures allow the discovery of coumarins with expanded chemical space. The ability to exert noncovalent interactions with many enzymes and receptors in live organisms lead the coumarins to exhibit a wide range of biological activities and applications.

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Coffee is one of the main food products commercialized in the world. Its considerable market value among food products makes it susceptible to adulteration, especially with cereals. Therefore, the objective of this study was to develop a method based on Real-Time Polymerase Chain Reaction (PCR) for detection of cereals in commercial ground roast and soluble coffees.

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