Publications by authors named "Felipe Rocha"

Babassu oil (BO) was used in the production of oil in water (O/W) nanoemulsions in order to evaluate the potential application of an alternative source of vegetable oil in the composition of colloidal systems. The proportion of oil phase (10, 20 and 30 % w/w) and guar gum (GG) concentrations (0, 0.10, 0.

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Natural selection is known to favor specific gene combinations, thereby shaping the evolution of recombination rates, often through epistatic interactions. However, the dynamics of these interacting factors within natural populations remain poorly understood. In this study, we investigate the long-term maintenance of a complex polymorphism involving linked, nonoverlapping chromosomal inversions in a natural population of .

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Pre-exposure prophylaxis (PrEP) is an effective HIV prevention strategy that consists in the use of antiretroviral drugs by seronegative people at risk of HIV. Negative perceptions, inadequate understanding, and access barriers have been associated with decreased medication adherence. Manaus is the largest city in the Brazilian Amazon, where the incidence of HIV/AIDS is high, and the rates of adherence to the antiretroviral treatment for HIV and PrEP are low.

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One Health (OH) is an integrative approach to human, animal, and environmental health and can be used as a comprehensive indicator for comparative purposes. Although an OH index has been proposed for comparing cities, states, and countries, to date, no practical study has compared countries using this approach. Accordingly, this study aimed to assess OH initiatives using a survey with a veterinary public health focus.

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In 2018, an outbreak of human rabies caused by the hematophagous bat hit the Brazilian Amazon Basin community of Melgaço, Brazil, resulting in the death of 10 people, 9 of them children. The incidence of rabies has been on the rise among populations in conditions of vulnerability in this ecosystem due to human expansion into sylvatic environments and limited access to public health services. To address this issue, in September 2019, a collaborative effort from national, local, and international institutions promoted and executed a pilot for pre-exposure prophylaxis of a population in high-risk areas for hematophagous bat-mediated rabies.

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Effective radical cure of Plasmodium vivax malaria is essential for malaria elimination in Brazil. P. vivax radical cure requires administration of a schizonticide, such as chloroquine, plus an 8-aminoquinoline.

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Introduction And Purpose: Basilar artery occlusion (BAO) is still one of the most devastating neurological conditions associated with high morbidity and mortality. In the present study, we aimed to assess the role of posterior circulation collaterals as predictors of outcome in the BASICS trial and to compare two grading systems (BATMAN score and PC-CS) in terms of prognostic value.

Methods: We performed a sub-analysis of the BASICS trial.

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Background: The best strategy to achieve optimal reperfusion outcomes during mechanical thrombectomy remains to be defined. The RapidPulse Cyclic Aspiration System is a novel technology, delivering high-frequency pulsed vacuum forces to increase the efficiency of aspiration thrombectomy.

Methods: Prospective, multicenter, open-label, core lab-adjudicated, two-arm study comparing safety and efficacy of a feasibility version of the RapidPulse system compared with contemporary controls.

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Article Synopsis
  • - Larrea nitida Cav. is a plant native to Argentina and Chile, known for its antimicrobial properties that can help control agricultural pathogens, but its extract is hydrophobic, limiting its effectiveness in water.
  • - Researchers used solid dispersion techniques to create water-soluble nanodispersions of the extract combined with polyethylene glycol (PLE) and zinc acetate (PZLE), testing their fungicidal activity against specific plant pathogens.
  • - The study found that the nanoparticles were effective in inhibiting the growth of harmful fungi, with PZLE showing better results than PLE, highlighting their potential as eco-friendly solutions in agriculture that need further exploration.
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Lima, Peru, has not had a case of canine rabies since 1999. However, Lima remains at risk of rabies reintroduction due to the free movement of dogs from nearby rabies-endemic areas. In Latin America, rabies vaccination campaigns must reach 80% of dogs to halt transmission, but estimates of vaccine coverage are often unavailable, unreliable, or inaccurate.

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The oil extracted from baru (Dipteryx alata Vog.) seeds is in bioactive compounds and it presents potential to be used in food and cosmetic industries. Therefore, this study aims to provide insights into the stability of baru oil-in-water (O/W) nanoemulsions.

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Introduction: The relationship between sleep quality and rest location is rarely explored in the literature. In this context, ergonomic analysis instruments can contribute with information for a satisfactory rest environment throughout the work schedule.

Objectives: To analyze the performance of an instrument based on Ergonomic Workplace Analysis for assessing rest locations.

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In the Brazilian Amazon, deaths and disabilities from snakebite envenomations (SBEs) are a major and neglected problem for the indigenous population. However, minimal research has been conducted on how indigenous peoples access and utilize the health system for snakebite treatment. A qualitative study was conducted to understand the experiences of health care professionals (HCPs) who provide biomedical care to indigenous peoples with SBEs in the Brazilian Amazon.

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Article Synopsis
  • * Diagnosis of CJD involves assessing clinical symptoms alongside brain imaging, electroencephalogram results, and cerebrospinal fluid analysis for specific markers.
  • * A case study of a 53-year-old patient in Fortaleza, Brazil, confirmed a probable diagnosis of sporadic CJD using tests for 14-3-3 protein and RT QUIC analysis, ruling out other similar conditions.
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Natural pigments are bioactive compounds that can present health-promoting bioactivities in the human body. Due to their strong coloring properties, these compounds have been widely used as color additives as an alternative to artificial colorants. However, since these pigments are unstable under certain conditions, such as the presence of light, oxygen, and heat, the use of complexation and encapsulation techniques with biopolymers is in demand.

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The Covid-19 pandemic has strongly impacted people's lives and the food industry. In this sense, food products claiming nutritional and health-promoting benefits due to the presence of bioactive peptides and probiotics, such as Greek-style yogurt, have been in demand. The objective of this work was to investigate, through word association, the perception of the consumers regarding the seven concepts related to Greek-style yogurt (traditional, ultra-creamy, zero fat, high content proteins, zero lactose, light and with no added sugars), in the context of social isolation due to Covid-19.

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Essential oils (EOs) have been considered potential green additives for active food packaging. However, sub-lethal concentrations of EOs may lead to bacterial resistance, which is a concern. In this sense, the effects of 1% (GEO1) and 10% (GEO10) of garlic EO in cellulose acetate-based films regarding homologous resistance in Listeria innocua were investigated after incubation at 37 °C/24 h and 7 °C/10 d.

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Red beetroot (Beta vulgaris L.) is a great source of betalains. The main betalains are the betacyanins, responsible for the purple color, and betaxanthins, which present a brownish color.

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Article Synopsis
  • Ants, particularly species from the Ponerinae subfamily, have complex relationships with various microorganisms like bacteria, which are essential for understanding their ecology.
  • Researchers focused on two trap-jaw ant species, Odontomachus chelifer and Odontomachus hastatus, to analyze their bacterial communities in different habitats (the Brazilian savanna and Atlantic rainforest).
  • The study found that the structure of these bacterial communities varied significantly based on both habitat and species, with differences in diversity and specific bacterial types present in the cuticle and gaster of the ants.
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Objectives: Truck drivers' work organization requires that rest and sleep be taken in various locations, where sleep quality might be affected by the discomfort of these environments. The purpose of this study was to evaluate truck drivers' rest locations and their association with sleep quality utilizing an ergonomic approach.

Material And Methods: The sleep quality of 81 truck drivers was assessed using the Pittsburgh sleep quality index (PSQI).

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Rabies is listed as one of the World Health Organisation's (WHO) Neglected Tropical Diseases Worldwide, with a significant impact in South America. This paper explores the dynamics of rabies cases in humans, pets (dogs and cats), livestock and wildlife (bats in particular) in South America during the period 2009-2018. The data used in this study were derived from the two main databases for rabies in South America: the OIE-WAHIS from the World Organisation for Animal Health (OIE) and PANAFTOSA's Regional Information System for the Epidemiological Surveillance of Rabies (SIRVERA).

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Article Synopsis
  • Headache is a common symptom in COVID-19, affecting 6.5% to 34% of patients, but previous studies often included unverified cases or focused on severe cases.
  • The study analyzed 24 laboratory-confirmed COVID-19 patients who reported headaches, revealing that the average age was 53.8 years and most had no prior history of headaches.
  • The headaches were mainly bifrontal or holistic, of a pressure quality, typically began early in illness, and worsened with physical activity, but no unique characteristics were found to distinguish them from other headache causes.
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Background Identification of large vessel occlusion (LVO) is critical to the management of acute ischemic stroke and prerequisite to endovascular therapy in recent trials. Increasing volumes and data complexity compel the development of fast, reliable, and automated tools for LVO detection to facilitate acute imaging triage. Purpose To investigate the performance of an anterior circulation LVO detection platform in a large mixed sample of individuals with and without LVO at cerebrovascular CT angiography (CTA).

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Objective: To evaluate the correlation between knee axis and hindfoot axis in patients with advanced gonarthrosis, and the association between ankle function and angular deformities.

Methods: 72 patients were enrolled in the study: 66% were women, and mean age was 58.7 years.

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Background: Small and remote acute ischemic lesions may occur in up to one-third of patients with spontaneous intracerebral hemorrhage (ICH). Possible mechanisms include cerebral embolism, small vessel disease, blood pressure variability and others. The embolic mechanism has not been adequately studied.

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