Publications by authors named "Felipe Pinheiro Vilela"

Article Synopsis
  • The study aimed to analyze the global genomic characteristics of 86 Salmonella Gallinarum and Pullorum genomes, which are significant pathogens in poultry.
  • Key findings revealed the presence of multiple resistance genes and virulence factors, along with various plasmids and prophages, indicating a high level of genetic diversity among the strains.
  • Multilocus sequence typing (MLST) and core genome MLST (cgMLST) successfully differentiated strains by biovar and geography, illustrating both local and global distributions.
View Article and Find Full Text PDF

Yersinia is an important genus comprising foodborne, zoonotic and pathogenic bacteria. On the other hand, species of the so-called group Yersinia enterocolitica-like are understudied and mostly characterized as non-pathogenic, despite of some reports of human infections. The present study aimed to provide genomic insights of Yersinia frederiksenii (YF), Yersinia intermedia (YI) and Yersinia kristensenii (YK) isolated worldwide.

View Article and Find Full Text PDF

Stenotrophomonas maltophilia (S. maltophilia) is an intrinsically drug-resistant and biofilm-forming bacteria causing infections in immunocompromised humans. This study reports the isolation of five S.

View Article and Find Full Text PDF

Salmonella enterica serovar Infantis (S. Infantis) is a globally distributed non-typhoid serovar infecting humans and food-producing animals. Considering the zoonotic potential and public health importance of this serovar, strategies to characterizing, monitor and control this pathogen are of great importance.

View Article and Find Full Text PDF

Aims: Our aim is to characterize through whole-genome sequencing (WGS) the antimicrobial resistance (AMR) and heavy metal tolerance (HMT) genes content, plasmid presence, virulence potential and genomic diversity of the rare non-typhoid Salmonella enterica serovar Orion (S. Orion) from 19 countries of the African, American, Eastern Mediterranean, European, Southeastern Asia and Western Pacific regions.

Methods And Results: Totally 324 S.

View Article and Find Full Text PDF

Salmonella 1,4, [5],12:i:- is one of the most prevalent serovars associated with gastroenteritis in several countries, including Brazil. However, few studies have analyzed the virulence potential of this variant in this country. Therefore, this study aimed to characterize S.

View Article and Find Full Text PDF

serovar Isangi (. Isangi) is a rare non-typhoidal serovar, related to invasive nosocomial infections in various countries and to increasing antimicrobial resistance rates. Despite existing reports on .

View Article and Find Full Text PDF

Salmonella enterica serovar Heidelberg (S. Heidelberg) is a zoonotic, ubiquitous, and worldwide-distributed pathogen, responsible for gastroenteritis in humans caused by the consumption of contaminated food. In this study, 11 S.

View Article and Find Full Text PDF
Article Synopsis
  • S. Infantis is a globally distributed, non-typhoid foodborne pathogen linked to rising antimicrobial resistance, often due to mechanisms like efflux pumps and heavy metal tolerance genes.
  • The study analyzed 80 S. Infantis strains from various sources in Brazil to determine the prevalence of these resistance genes and their genetic relationships through core-genome multi-locus sequence typing (cgMLST).
  • Results revealed a high occurrence of efflux pump and heavy metal tolerance genes, emphasizing the need for robust surveillance to monitor resistance and prevent transmission in diverse environments.
View Article and Find Full Text PDF
Article Synopsis
  • Salmonella enterica serovar Choleraesuis (S. Choleraesuis) is a type of bacteria that can cause serious infections in humans and is commonly found in pigs; however, information about this bacteria in Brazil is limited.
  • In this study, six strains of S. Choleraesuis from both animals and a human were analyzed for antibiotic resistance, revealing significant resistance to various antibiotics and the presence of several resistance genes and plasmids.
  • The findings highlight the importance of improved monitoring of S. Choleraesuis to prevent its spread from animals to humans, as the strains showed strong resistance profiles and genetic similarities to other local strains.
View Article and Find Full Text PDF
Article Synopsis
  • The study focuses on Salmonella Dublin, a cattle-related bacteria that occasionally causes illness in humans, particularly analyzing strains from Brazil and other countries.
  • Whole genome sequencing (WGS) of 112 Brazilian strains and 87 international strains identified three clades, with Brazilian strains divided into two clades (A and C) and displaying unique genetic features.
  • Brazilian strains exhibited specific antimicrobial resistance genes and plasmids, highlighting the bacterial strains' varied virulence and genetic makeup, which underscores the potential zoonotic risk associated with S. Dublin circulating in Brazil for over 30 years.
View Article and Find Full Text PDF

Aims: To characterize the genetic relatedness, phenotypic and genotypic antimicrobial resistance and plasmid content of 80 Salmonella Infantis strains isolated from food, humans and veterinary sources from 2013 to 2018 in Brazil.

Methods And Results: Pulsed-field gel electrophoresis and single-nucleotide polymorphism analysis showed major clusters containing 50% and 38.8% of the strains studied respectively.

View Article and Find Full Text PDF

species are important environmental-related bacteria responsible for diverse infections in humans due to consumption of contaminated water and seafood in underdeveloped areas of the world. This study aimed to investigate the frequency of antimicrobial resistance genes in 577 sequenced and strains isolated in Latin American countries available at the NCBI Pathogen Detection database and to determine the sequence type (ST) of the strains. Almost all strains studied (99.

View Article and Find Full Text PDF

Salmonella Typhimurium (ST313) has caused an epidemic of invasive disease in sub-Saharan Africa and has been recently identified in Brazil. As the virulence of this ST is poorly understood, the present study aimed to (i) perform the RNA-seq in vitro of S. Typhimurium STm30 (ST313) grown in Luria-Bertani medium at 37°C; (ii) compare it with the RNA-seq of the S.

View Article and Find Full Text PDF

Salmonella enterica serovar Infantis is a broadly distributed serovar infecting humans and animal reservoirs globally. Here, we report 80 draft genome sequences of . Infantis strains isolated from diverse sources in Brazil.

View Article and Find Full Text PDF

Salmonella Dublin is a strongly cattle-adapted serovar that has also been responsible for severe invasive infections in humans. Although invasive infections by non-typhoid Salmonella have increased in developed and in developing countries, in sub-Saharan Africa these infections have been frequently related to Salmonella Typhimurium strains from Sequence Type (ST) 313 that harbor a possible virulence marker, the bstA gene, broadly detected in S. Dublin strains.

View Article and Find Full Text PDF

is an order of bacteria responsible for community and hospital-acquired infections related to high rates of antimicrobial resistance and increased treatment costs, morbidity, and mortality globally. The aims of this study were to analyze the frequency of the resistance genes detected and distribution over the years and sources of isolation in sequenced strains isolated in Brazil and available at the Pathogen Detection website. The presence of resistance genes was analyzed in 1,507 whole-genome sequenced strains of 19 species.

View Article and Find Full Text PDF

Salmonella Dublin is a strongly adapted serovar that causes enteritis and/or systemic disease with high rates of mortality in cattle and occasionally infects humans. Despite the importance of this serovar, there is a lack of studies in Brazil. The aim of this study was to characterize the genetic diversity of 112 S.

View Article and Find Full Text PDF

Resistance of Salmonella Dublin strains to quinolones and tetracycline has been increasing worldwide. Studies regarding the genotypic resistance traits of strains of this serovar isolated in Brazil are scarce. This study aims to examine the genetic characteristics of Salmonella Dublin strains isolated in Brazil, which are associated with resistance to quinolone and tetracycline.

View Article and Find Full Text PDF

serovar Dublin is a strongly adapted serovar that causes enteritis and/or systemic disease in cattle and results in high rates of mortality. Here, we report the draft genome sequences of 112 Dublin strains isolated from humans and animals in Brazil. These draft genome sequences will help enhance our understanding of this serovar in Brazil.

View Article and Find Full Text PDF