Publications by authors named "Felipe E de Carvalho"

Background: The profitability of the beef industry is directly influenced by the fertility rate and reproductive performance of both males and females, which can be improved through selective breeding. When performing genomic analyses, genetic markers located on the X chromosome have been commonly ignored despite the X chromosome being one of the largest chromosomes in the cattle genome. Therefore, the primary objectives of this study were to: (1) estimate variance components and genetic parameters for eighteen male and five female fertility and reproductive traits in Nellore cattle including X chromosome markers in the analyses; and (2) perform genome-wide association studies and functional genomic analyses to better understand the genetic background of male and female fertility and reproductive performance traits in Nellore cattle.

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  • Climate change is increasingly threatening the livestock industry by affecting animal productivity, welfare, and management, prompting a focus on enhancing livestock's climatic resilience (CR).
  • A study performed genome-wide association studies on lactating sows under heat stress, identifying 31 significant single nucleotide polymorphisms (SNPs) linked to nine CR indicators and revealing that CR is a polygenic trait with small effect sizes across various chromosomes.
  • Key candidate genes related to heat stress response and various physiological processes were identified, along with relevant pathways indicating links to stress, immune responses, and various traits like health and production quality in livestock.
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  • Researchers analyzed vaginal temperature data from lactating sows to create 15 new indicators of climatic resilience (CR) to improve pig breeding, particularly during heat stress periods.
  • Heritability estimates for CR traits varied, with some traits showing moderate to high genetic correlations with key reproductive traits and indicators of heat stress.
  • Sows with higher genomic estimated breeding values (GEBV), indicating they are more sensitive to climate conditions, tended to have higher skin temperature and respiration rates, but lower body condition scores compared to those with lower GEBV, suggesting differences in resilience.
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We explored the influence of maternal nutritional strategies on the development of the rumen and cecum in offspring. Additionally, we investigated the potential repercussions of prenatal nutrition on the rumen and fecal microbiota composition, utilizing metagenomic 16S techniques, to understand the effects of fetal programming (FP) in Nellore cattle. A total of 63 bulls submitted to different prenatal nutrition strategies, namely, non-programming (NP), partial programming (PP), and complete programming (CP), were evaluated.

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