Publications by authors named "Felipe Barjud Pereira do Nascimento"

Context: Invasive and somatostatin receptor ligand (SRL)-resistant pituitary tumors represent a challenge in the clinical practice of endocrinologists. Efforts have been made to elucidate reliable makers for both. Survivin and eukaryotic translation initiation factor-binding protein 1 (4EBP1) are upregulated in several cancers and involved in apoptosis and cell proliferation.

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The 1° Encontro Latino-Americano de IA em Saúde (1st Latin American Meeting on AI in Health) was held during the 2022 Jornada Paulista de Radiologia, the annual radiology meeting in the state of São Paulo. The event was created to foster discussion among Latin American countries about the complexity, challenges, and opportunities in developing and using artificial intelligence (AI) in those countries. Technological improvements in AI have created high expectations in health care.

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The cranial nerves, which represent extensions of the functional structures of the brain, traverse the head and neck. They are connected to various cranial structures and are associated with several diseases. An in-depth understanding of their complex anatomy and normal imaging appearance allows the examiner to identify and characterize abnormalities with greater precision.

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The cranial nerves, which represent extensions of the functional structures of the brain, traverse the head and neck. They are connected to various cranial structures and are associated with several diseases. An in-depth understanding of their complex anatomy and normal imaging appearance allows the examiner to identify and characterize abnormalities with greater precision.

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Article Synopsis
  • The study investigates the clinical and genetic factors associated with non-syndromic pituitary gigantism (PG) in 18 patients from a tertiary center in Brazil.
  • Genetic testing revealed pathogenic variants in the AIP gene in 25% of patients, with two female patients diagnosed with X-LAG due to GPR101 microduplication.
  • The findings highlight differences in symptom onset and diagnosis between AIP and GPR101 patients, but overall clinical features and treatment outcomes were similar across the cohort.
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  • The study aimed to quantitatively analyze brain volume changes in elderly individuals using MRI scans from a sample of 525 participants aged 60 to 103 in São Paulo, Brazil.
  • Results showed that total brain volume decreases by approximately 2.4% every decade post-60, with both gray and white matter experiencing reductions.
  • The findings support previous research from the U.S. and Europe, revealing gender differences in brain volume ratios, which could bias assessments of brain atrophy based on cerebrospinal fluid space evaluations.
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The rheumatic diseases, which include systemic lupus erythematosus, rheumatoid arthritis, Behçet's disease, scleroderma, and ankylosing spondylitis, are characterized by involvement of connective tissue, with multiple manifestations. In those diseases, there can be involvement of the peripheral or central nervous system, and that involvement can be primary, presenting as a major feature of the clinical presentation, or secondary, as an effect of the drugs used in order to control a given disease or its complications. Knowledge of the wide variety of imaging findings is crucial to the diagnosis of a rheumatic disease, especially in the early stages, enabling effective treatment and minimizing disability.

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Objective: To assess the magnetic resonance imaging (MRI) patterns associated with central nervous system infection with sp. in relation to patient immune status.

Materials And Methods: This was a retrospective study of MRI data for 19 patients with neurocryptococcosis who underwent the examination between January 2000 and March 2014.

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Objectives: Our goal was to estimate the diagnostic accuracy of substantia nigra fractional anisotropy (SN-FA) for Parkinson's disease (PD) diagnosis in a sample similar to the clinical setting, including patients with essential tremor (ET) and healthy controls (HC). We also performed a systematic review and meta-analysis to estimate mean change in SN-FA induced by PD and its diagnostic accuracy.

Methods: Our sample consisted of 135 subjects: 72 PD, 21 ET and 42 HC.

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The cardiac chamber's involvement with neoplastic embolism has been rarely reported; it is mostly associated with gastric, breast, lung, liver, and prostate cancers, and usually affects the pulmonary arteries. This paper reports a case of a 31-year-old man with a malignant testicular germ cell tumor who presented with multiple episodes of pulmonary thromboembolism and died of sudden respiratory failure 1 year after the initial diagnosis. Death was attributed to massive pulmonary embolism and pulmonary infarction associated with a neoplastic thrombus that extended from the gonadal veins to pulmonary arteries.

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Article Synopsis
  • This study discusses the use of postmortem computerized tomographic angiography (PMCTA) in identifying the source of bleeding after surgery in a patient with giant juvenile nasopharyngeal angiofibroma.
  • The case showed that PMCTA successfully detected the bleeding source, which conventional autopsy failed to find, indicating PMCTA's effectiveness in forensic investigations.
  • The authors highlight the importance of incorporating PMCTA as a routine procedure in forensic medicine to better pinpoint causes of fatal hemorrhage.
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