Publications by authors named "Felipe Arroyave"
Article Synopsis
- - Diabetes mellitus leads to various complications, but researchers are exploring the creation of pancreatic β-like cells (PβLCs) from induced pluripotent stem cells (iPSCs) as a potential treatment.
- - Current methods for differentiating iPSCs into pancreatic β cells aim to mimic natural pancreatic development using specific combinations of cytokines and small molecules to activate necessary signaling pathways.
- - This study presents a new protocol that effectively produces PβLCs with essential characteristics of pancreatic β cells, including insulin secretion and the expression of important markers, enhanced by the addition of vitamin C and retinoic acid during differentiation.
Adipose tissue is the largest endocrine organ in humans and has an important influence on many physiological processes throughout life. An increasing number of studies have described the different phenotypic characteristics of fat cells in adults. Perhaps one of the most important properties of fat cells is their ability to adapt to different environmental and nutritional conditions.
View Article and Find Full Text PDFDiabetes mellitus (DM) is one of the main causes of morbidity and mortality, with an increasing incidence worldwide. The impact of DM on public health in developing countries has triggered alarm due to the exaggerated costs of the treatment and monitoring of patients with this disease. Considerable efforts have been made to try to prevent the onset and reduce the complications of DM.
View Article and Find Full Text PDF