Cost Effectiveness of Intracranial Pressure Monitoring in Pediatric Patients with Severe Traumatic Brain Injury: A Simulation Modeling Approach.

Objectives: To conduct an economic evaluation of intracranial pressure (ICP) monitoring on the basis of current evidence from pediatric patients with severe traumatic brain injury, through a statistical model.

Methods: The statistical model is a decision tree, whose branches take into account the severity of the lesion, the hospitalization costs, and the quality-adjusted life-year for the first 6 months post-trauma. The inputs consist of probability distributions calculated from a sample of 33 surviving children with severe traumatic brain injury, divided into two groups: with ICP monitoring (monitoring group) and without ICP monitoring (control group).

[Monitoring intracranial pressure in severe traumatic brain injury].

Introduction: Severe traumatic brain injury (TBI) is a serious condition. Intracranial pressure (ICP) monitoring can be used to direct treatment, which is of limited access in developing countries.

Objective: To describe the clinical experience of pediatric patients with severe TBI.

[Confounding effect of prematurity in the neonatal death associated with obstetric maternal morbidity].

Background: Prematurity is considered the main factor of neonatal mortality in developed countries (60 to 80% of cases).

Objective: To determine if obstetric morbidity and/or prematurity are associated with neonatal death.

Patients And Methods: A cohort of 25,365 live newborns since January 1st 2000 to December 31st 2004 was studied.

[Impact of maternal antecedents on neonatal mortality in a regional perinatal hospital].

Objective: Determine the prevalence of maternal risk factors and evaluate their impact on neonatal mortality in a regional perinatal center.

Materials And Methods: A cohort of 25,365 live newborns was studied between January 1st 2000 and December 31st 2004. Maternal antecedents were registered in a data base: sociodemographic; medical history; obstetric antecedents of previous pregnancies; as well as evolution of current pregnancy and birth.

[Maternal history impact in neonatal mortality].

Background: Perinatal clinical picture allows identifying psychosocial features in pregnant women, them medical, obstetrical, and pregnancy history, present delivery, and neonatal mortality risk factors.

Objective: To know prevalence of maternal risk factors and evaluates them impact on neonatal mortality.

Materials And Methods: A cohort of 25,365 live newborns was studied between January 1st 2000 and December 31st 2004.

Discriminant function of perinatal risk that predicts early neonatal morbidity: its validity and reliability.

Background: This study aimed to identify significant perinatal risk factors associated with neonatal morbidity to construct a scoring system to aid in distinguishing between healthy and ill neonates. Validity and reliability of the scoring system were determined.

Methods: We conducted a screening test and used logistic regression to analyze data from a cohort of 387 neonates and to determine the relationship between risk factors and morbidity.