Publications by authors named "Felicitas Engel"

The prevalence of chronic pain is increasing, and conventional pain therapies often have limited efficacy in individuals with high levels of psychological distress and a history of trauma. In this context, the use of Eye Movement Desensitization and Reprocessing (EMDR), an evidence-based psychotherapy approach for the treatment of posttraumatic stress disorder, is becoming increasingly important. EMDR shows promising results, particularly for patients with pain and high levels of emotional distress.

View Article and Find Full Text PDF

Objective: Somatic symptom disorder (SSD) is one of the most common reasons for consultations in primary care, in addition to simple acute infections. Questionnaire-based screening instruments to identify patients at high risk of SSD are thus of great clinical relevance. Although screening instruments are frequently used, it is currently unclear to what extent they are influenced by the concurrent presence of simple acute infections.

View Article and Find Full Text PDF

Irritable bowel syndrome (IBS) is a gut-brain disorder of multifactorial origin. Evidence of disturbed serotonergic function in IBS accumulated for the 5-HT receptor family. 5-HTRs are encoded by HTR3 genes and control GI function, and peristalsis and secretion, in particular.

View Article and Find Full Text PDF

Objective: Irritable bowel syndrome (IBS) is a chronic disease leading to abdominal pain that is often related to psychological distress. The aim of the study was to investigate the temporal relationships between abdominal pain and psychological variables in patients with IBS.

Methods: This longitudinal diary study included eight patients from a waiting group, recruited in the frame of a pilot intervention study.

View Article and Find Full Text PDF

Background: Single-nucleotide polymorphisms (SNPs) of the serotonin type 3 receptor subunit () genes have been associated with psychosomatic symptoms, but it is not clear whether these associations exist in irritable bowel syndrome (IBS).

Aim: To assess the association of polymorphisms with depressive, anxiety, and somatization symptoms in individuals with IBS.

Methods: In this retrospective study, 623 participants with IBS were recruited from five specialty centers in Germany, Sweden, the United States, the United Kingdom, and Ireland.

View Article and Find Full Text PDF

Background: Irritable bowel syndrome (IBS) appears to have a bidirectional interaction with both depressive and anxiety-related complaints. However, it remains unclear how exactly the psychological complaints, at the individual level, are related to somatic symptoms on a daily basis. This single case study investigates how somatic and psychological variables are temporally related in a patient with irritable bowel syndrome.

View Article and Find Full Text PDF

: Is there evidence for increased psychological distress and alterations in personality functioning in patients with Crohn's disease (CD) and ulcerative colitis (UC) compared to healthy controls (HCs)? : In patients with CD and UC, perceived stress is closely associated with changes in disease activity. The stress response is influenced by psychological burden and personality functioning, but only little is known about these factors in inflammatory bowel diseases (IBD). : A total of 62 patients with an endoscopic ensured CD/UC without remission ( = 31 per group) and 31 HC were included.

View Article and Find Full Text PDF
Article Synopsis
  • IBS is a gut-brain disorder where symptoms are influenced by a chemical called serotonin, and a particular gene related to serotonin (SLC6A4) may be involved in causing IBS.
  • Researchers found a specific gene change (called SNP rs2020938) that seems to be linked to constipation-predominant IBS, especially in females.
  • Further studies showed that this gene change affects how the SLC6A4 gene works in the intestines, which helps explain why it might be important for understanding IBS.
View Article and Find Full Text PDF

Objectives: Overlaps between different functional gastrointestinal disorders (FGIDs) are common. However, little is known about the impact of this overlap on patients' health status. This study is aimed at analyzing the differences between patients with multiple as compared to one single FGID.

View Article and Find Full Text PDF