Natural History of Dilated Cardiomyopathy Due to in Emerin Protein.

(1) : Dilated cardiomyopathy (DCM) mainly affects young individuals and is the main indication of heart transplantation. The variant of the gene coding for emerin in chromosome has been catalogued as a pathogenic variant for the development of DCM, exhibiting an X-linked inheritance pattern. (2) : A retrospective study was conducted covering the period 2015-2023 in patients with DCM of genetic origin.

Hepatitis C virus infection screening reduces mortality and is cost-effective independently of the intervention test.

Introduction: Chronic infection due to hepatitis C virus (HCV) is frequently asymptomatic even in advanced stages of liver disease. Implementation of a screening program based on different HCV tests may enable an earlier diagnosis of HCV liver disease and subsequent application of highly effective treatment.

Patients And Methods: A Markov model which compares three different screening strategies for hepatitis C versus no screening in low-risk prevalence (general population) and high-risk prevalence population (people who inject drugs or prison population) was designed, taking into account age at the start of screening and participation.

[Beginnings, evolution and current situation of the Newborn Screening Programs in Spain.].

Newborn Screening Programs (NSP) in Spain were born in the city of Granada in 1968. Till the 1980s, they were developed around the so-called "National Plan for Preventing Subnormality", covering up to 30% of the Spanish newborns. From 1982, when the health system management was transferred to the different autonomous regions, the NSP began to expand, and the bases to transform them into an organized and multidisciplinary activity, integrated and coordinated from the National Health System were settled.