Publications by authors named "Felicia Lindberg"
Background: Gamma Knife radiosurgery (GKRS) is a well-established treatment for residual or growing pituitary adenomas (PAs) post-partial resection. However, some PAs grow even after initial GKRS, for which the efficacy of repeat GKRS is unclear. The primary objective of this study was to determine long-term progression-free survival (PFS) following repeated GKRS in patients with PA.
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- Pituitary adenomas often lead to the need for Gamma Knife radiosurgery (GKRS) after incomplete removal or recurrence, and this study aims to assess its long-term effectiveness.
- In a cohort study of 147 patients who underwent GKRS between 1999 and 2020, the researchers evaluated progression-free survival (PFS) over an average follow-up of 8.1 years, finding a 5-year PFS of 86% and a 10-year PFS of 68%.
- Results indicated that somatotrophic adenomas had lower progression risks, but 32% of patients experienced adverse radiation events, mainly hypopituitarism, highlighting the need to weigh outcomes against potential side effects.