A prospective study to assess the effectiveness and safety of the BlueWind System in the treatment of patients diagnosed with urgency urinary incontinence.

Background: Overactive bladder (OAB) affects one in six adults in Europe and the United States and impairs the quality of life of millions of individuals worldwide. When conservative management fails, third-line treatments including tibial neuromodulation (TNM) is often pursued. TNM has traditionally been accomplished percutaneously in clinic.

Surgical Case Logging Habits and Attitudes: A Multispecialty Survey of Residents.

Objective: The Accreditation Council for Graduate Medical Education measures surgical residents' experience in the United States by mandating that residents log each procedure in which they have participated. This system is the primary mechanism by which breadth and depth of surgical training are documented, and data are used for program accreditation and by individual program directors to assess resident preparedness. The study objective was to learn from residents across surgical specialties how this system is being used, and whether they believe these data are reliable.

The effect of age and medical comorbidities on in vitro myoblast expansion in women with and without pelvic organ prolapse.

Introduction: This is an observational study is designed to assess the influence of age, prolapse and medical co-morbidities on myogenic stem cells growth in-vitro.

Methods: A biopsy of the rectus abdominus muscle was obtained during surgery in patients with and without pelvic organ prolapse (POP). Nuclei number and fiber count were correlated with patient's age, presence of POP, and medical comorbidities.

Safety assessment of myogenic stem cell transplantation and resulting tumor formation.

Objectives: To assess for stem cell migration to liver and lung after transplantation in injured rat anal sphincters. To evaluate histological findings of unanticipated ectopic foci of growth.

Methods: This is a prospective study involving 33 female virginal Sprague-Dawley rats.

In vivo recovery of the injured anal sphincter after repair and injection of myogenic stem cells: an experimental model.

Objective: This study aims to evaluate in vivo function of the external anal sphincter after transection and repair augmented with myogenic stem cells, and to establish normative electromyography parameters of the rodent external anal sphincter.

Design And Setting: Thirty-three Sprague-Dawley rodents underwent baseline needle electromyography of the external anal sphincter. Motor unit action potentials were obtained and normative parameters established.

Randomized prospective crossover study of interstim lead wire placement with curved versus straight stylet.

Aims: To assess whether InterStim lead wire placement with the curved stylet achieves motor response at lower amplitudes compared to straight stylet use.

Methods: This was a prospective, randomized, crossover study of patients scheduled for InterStim lead wire placement. All patients underwent lead wire testing with both the curved and straight stylets.

Stem cells in gynecology.

Stem cell based therapies hold promise for the obstetrician and gynecologist. This article reviews the history of stem cells and some of their current applications in gynecology. Currently, mesenchymal and muscle-derived stem cells are being explored for the treatment of urinary and anal incontinence.

Ischiorectal fossa abscess after pelvic floor injection of botulinum toxin.

Botulinum toxin is used to treat pelvic floor tension myalgia; however, its safety profile is poorly understood. We report an ischiorectal fossa abscess after pelvic floor injections of botulinum toxin. Physicians need to be aware of this possible complication, consider alternate injection techniques and antiseptic preparation before injection.

Use of composite grafts in abdominal sacrocolpopexy.

Objective: : The ideal graft material for pelvic reconstructive surgery remains undetermined. The purpose of this study was to present data on novel composite biologic/synthetic grafts during use in abdominal sacrocolpopexy.

Methods: : A case series of 90 patients undergoing abdominal sacrocolpopexy with composite biologic/synthetic grafts was conducted.

Allogenic myoblast transplantation in the rat anal sphincter.

Objectives: : To determine the feasibility of injecting rat myoblasts into the intact anal sphincter as a potential treatment for anal incontinence, and to detect transferred myoblast survival and integration.

Study Design: : A pilot study using nonpregnant female Sprague Dawley rodents of 8 to 10 weeks of age. A biopsy of skeletal muscle was harvested from a study animal and recovered myoblasts were expanded in vitro over 10 days.

Reconstructive pelvic surgery and plastic surgery: safety and efficacy of combined surgery.

Objective: The purpose of this study was to address the safety of combining aesthetic and pelvic floor reconstructive procedures.

Study Design: Fifty-four subjects were included in a case-control study; 18 patients undergoing combined pelvic and plastic reconstructive surgery, age and procedure matched to 18 pelvic surgery and 18 plastic surgery only controls. Chi-square, t test, and Kruskal-Wallis analysis were used to compare the estimated blood loss (EBL), body mass index (BMI), hospital days, operative times, and complications between the groups.

Effects of the incontinence dish pessary on urethral support and urodynamic parameters.

Objective: To evaluate the effects of the incontinence dish pessary (IDP) on urethral mobility and urodynamics.

Study Design: Prospective study of women with symptoms of stress incontinence. Q-tip test was performed recording the resting and straining angles with and without an IDP.

Lynx midurethral sling system: a 1-year prospective study on efficacy and safety.

The objective of this study is to determine the outcomes for the Lynx midurethral sling system in the treatment of urodynamic stress incontinence (USI). Prospective study of 118 subjects who underwent a Lynx midurethral sling procedure for USI. Subjects were considered cured if they were subjectively dry by history and objectively dry by standing stress test.

Repairing perineal hernia.

The patient's pelvic structures repeatedly shifted out of place. Her physicians found a fix that helped.

Sacral nerve neuromodulation in patients with underlying neurologic disease.

Objective: Sacral nerve neuromodulation (SNS) is an effective treatment for lower urinary tract dysfunction. Many underlying neurologic processes affect lower urinary tract function. We present results of SNS in patients with underlying neurologic dysfunction.

Sacral nerve neuromodulation in patients with cardiac pacemakers.

Objective: The objective of the study was to describe our experience using sacral nerve neuromodulation for urinary urgency, frequency, and urge incontinence in patients with cardiac pacemakers.

Study Design: The study was a case series of 3 patients with cardiac pacemakers who underwent sacral nerve stimulation for refractory urgency, frequency, and urge incontinence.

Results: Each patient underwent placement of an InterStim lead wire in the S3 foramen.

Does pelvic organ prolapse quantification exam predict urethral mobility in stages 0 and I prolapse?

Objective: To determine if women with anterior support stages 0 or I by pelvic organ prolapse quantification (POP-Q) system require Q-tip testing to assess urethral mobility.

Methods: A prospective study of 134 women presenting for urogynecologic evaluation were examined and assigned stages of anterior wall support according to the POP-Q system. A Q-tip test was performed and urethral hypermobility was defined as a straining angle > or =30 degrees.